Medical Xpress

MAY 18, 2023

Diabetes researchers at Washington University School of Medicine in St. Louis have uncovered at least one reason insulin-secreting cells made from stem cells in the lab don't work as well as natural cells.

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Medical Xpress

MARCH 22, 2025

Jaeb Center for Health Research conducted a randomized controlled trial evaluating the impact of automated insulin delivery (AID) in adults with insulin-treated type 2 diabetes.

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BioSpace

AUGUST 19, 2020

Researchers from the Salk Institute took a major step forward in developing a new insulin-producing pancreatic cell cluster as a potential treatment for type 1 diabetes patients.

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pharmaphorum

JULY 14, 2021

Eli Lilly bought a stake in Protomer Technologies and its glucose-sensing insulin platform last year, and it must like what it has seen in the programme since then – it has just agreed to buy the company outright. . It was also responsible for the first recombinant insulin product – Humulin – which launched in 1982 and remains on sale.

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Drug Channels

SEPTEMBER 15, 2023

Nicole summarizes MMIT’s research on payers’ views of two crucial market changes: (1) the Inflation Reduction Act of 2022’s requirement to cap insulin prices at $35 for Medicare beneficiaries, and (2) manufacturers’ reduction in list prices for certain insulin products. Read on for Nicole’s insights.

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XTalks

JULY 3, 2023

The treatment is derived from deceased donor pancreatic cells and is indicated for patients who are unable to achieve average blood glucose levels (glycated hemoglobin) with daily insulin injections or with continuous infusion through a pump because of repeated episodes of severe hypoglycemia (low blood sugar).

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XTalks

SEPTEMBER 23, 2020

Being hailed as the world’s shortest and thinnest needle for insulin injection, Droplet Micron has recently been introduced into the pen needle market by HTL (High Tech Lab)-STREFA, Inc. These are important feature innovations for those that depend on insulin injections. The new and innovative needle measures at just 34G x 3.5mm.

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Scienmag

JANUARY 4, 2022

LA JOLLA—(January 4, 2022) The discovery of insulin 100 years ago opened a door that would lead to life and hope for millions of people with diabetes. Ever since then, insulin, produced in the pancreas, has been considered the primary means of treating conditions characterized by high blood sugar (glucose), such as diabetes.

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BioSpace

NOVEMBER 8, 2021

Research into Alzheimer’s disease is shifting from amyloid plaque and tau protein to neuroinflammation, white matter changes and insulin resistance.

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STAT News

MARCH 17, 2023

Enjoy, and see you soon … Following the lead of its rivals, Sanofi will cut the price of its most widely prescribed insulin in the U.S. The three companies are the largest manufacturers of insulin and collectively hold a dominant 80% share of the market. Continue to STAT+ to read the full story…

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Medical Xpress

FEBRUARY 20, 2023

Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion. Now, researchers want to investigate if it is possible to use the genetic CRISPR/Cas9 scissors to correct the gene's activity.

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Medical Xpress

APRIL 11, 2023

An international study shows that it is likely that insulin can be stored at room temperature, and for considerably longer than drug companies have counted on to date. Researchers at the University of Gothenburg are among the scientists presenting these results.

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Scienmag

JUNE 21, 2022

Diabetes is a lifelong, chronic health condition caused by abnormalities in the body’s production and use of the hormone insulin. Research has shown that the feel-good hormone, dopamine (DA), plays a key role in how the body regulates the production of insulin.

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Medical Xpress

FEBRUARY 16, 2023

Two classes of drugs prescribed off-label for some patients with type 1 diabetes can provide significant benefits, but also come with health concerns, according to a study by UT Southwestern Medical Center researchers.

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Drug Channels

JANUARY 10, 2023

Below, I highlight four takeaways from this year’s lists, including a look at biosimilar insulin and the forthcoming biosimilar competition for Humira. I also note some troubling research on the patient impact of exclusions—although much remains unknown. As always, I welcome your comments below or on social media.

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Drug Channels

MARCH 28, 2023

Below, I highlight four takeaways from this year’s lists, including a look at biosimilar insulin and the forthcoming biosimilar competition for Humira. I also note some troubling research on the patient impact of exclusions—although much remains unknown. As always, I welcome your comments below or on social media.

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Pharmaceutical Technology

JANUARY 10, 2023

The international T1D network TrialNet’s research was instrumental in the FDA’s approval of the first drug to delay T1D in at-risk people. Its research teams conducted the Teplizumab Prevention Study , which found that the drug could delay T1D for two or more years. Equity in early-stage testing.

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NY Times

NOVEMBER 27, 2021

A new treatment using stem cells that produce insulin has surprised experts and given them hope for the 1.5 million Americans living with the disease.

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Drug Channels

JANUARY 9, 2024

There are also unusual formulary developments for insulin products, many of which experienced massive list price cuts for 2024. I also highlight recent research that raises troubling questions about the patient impact of these ever-growing exclusion lists. Read on for my deep dive into these two therapeutic categories.

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XTalks

AUGUST 29, 2024

The recent US Food and Drug Administration (FDA) clearance of the Omnipod 5 Automated Insulin Delivery (AID) System for people with type 2 diabetes marks a significant milestone in diabetes care. The Omnipod 5 system offers a personalized approach to insulin delivery, integrating CGM with adaptive insulin administration.

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Camargo

OCTOBER 14, 2020

The FDA is planning two listening sessions to allow manufacturers, developers, health care providers, researchers, and other interested parties to learn more about the purpose and function of the DHCoE. Sign up here for the October or November listening sessions. FDA Issues Guidances Dealing with ANDAs.

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Scienmag

JUNE 7, 2021

A team of ETH researchers now wants to capitalise […]. The green light emitted, whether continuous or pulsed, penetrates the skin and can be used to measure the wearer’s heart rate during physical activity or while at rest. These watches have become extremely popular.

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Scienmag

DECEMBER 16, 2021

New research has taken an important step towards the goal for a treatment for the common diabetes complication hypoglycaemia, or low blood sugar. In all forms of diabetes, blood sugars become too high as the body is either unable to produce insulin, or cannot make enough of it, or the insulin it produces is not […].

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Pharma Times

DECEMBER 21, 2023

The new guidance followed a review of a clinical trial and real-world evidence by the University of Warwick and Warwick Medical School, funded by the National Institute for Health and Care Research. Additionally, adults with an average blood sugar of 7.5% or more will be issued the technology to maintain a level of 6.5%

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Scienmag

MAY 17, 2021

Findings point to possible treatment for smell loss Credit: Monell Chemical Senses Center, eNeuro PHILADELPHIA (May 17, 2021) – Researchers have known for some time that insulin plays a vital role in regeneration and growth in some types of neurons that relay environmental sensory information to our brains, such as sight.

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Pharmaceutical Commerce

MAY 28, 2024

The latest news for pharma industry insiders.

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Medical Xpress

FEBRUARY 2, 2023

In the ongoing research and treatment of diabetes, the focus is typically on the two forms of the disease that dominate public awareness. Type 1 has a stronger genetic component that requires insulin therapy for life; type 2 is frequently associated with obesity and lack of exercise resulting in insulin resistance.

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Scienmag

SEPTEMBER 29, 2021

Pancreatic beta cells produce, store and secrete insulin upon elevated blood glucose levels. However, the highly regulated process of insulin secretion, especially its molecular features and the stimuli behind this process have not yet been fully understood.

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STAT News

DECEMBER 20, 2022

Despite advancements in insulin treatments over the past three decades, disparities in outcomes have widened among people with diabetes taking them, a new study found.

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The Pharma Data

APRIL 28, 2022

Novo Nordisk today announced headline results from the ONWARDS 2 trial, a phase 3a, 26-week efficacy and safety treat-to-target trial investigating once-weekly insulin icodec vs insulin degludec in 526 people with type 2 diabetes switching from daily insulin. events per patient year exposed to once-weekly insulin icodec and 0.27

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XTalks

FEBRUARY 24, 2021

The injection experience is an often-overlooked aspect in insulin administration. For many daily insulin users, the experience is an important one, as it is directly related to quality of life and medication compliance. Related: Droplet Micron Insulin Needle Offers Innovation in Crowded Diabetes Supply Market.

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XTalks

OCTOBER 13, 2021

Researchers at the University of Toledo have developed a vaccine against inflammatory arthritis that has shown promise in animal models. The potential cybersecurity risk associated with the remote controllers could under- or over-deliver insulin to patients if an unauthorized user hacks into the system.

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BioSpace

JULY 12, 2022

A multinational research collaboration has developed a new peptide dubbed “PATAS”, which appears to fix the metabolic abnormalities leading to type 2 diabetes (T2D).

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The Pharma Data

JULY 29, 2021

Food and Drug Administration approved the first interchangeable biosimilar insulin product, indicated to improve glycemic control in adults and pediatric patients with Type 1 diabetes mellitus and in adults with Type 2 diabetes mellitus. Semglee (insulin glargine-yfgn) is the first interchangeable biosimilar product approved in the U.S.

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Velocity Clinical Research

JULY 27, 2023

Rosenstock has made remarkable strides in exploring what could be the world’s first once-weekly basal insulin. “In In ONWARDS 1, insulin icodec allowed people to spend significantly more Time in Range, with comparable Time below Range vs. once-daily basal insulin glargine U100,” said Dr. Rosenstock. “A

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XTalks

NOVEMBER 2, 2021

The government of Scotland has rolled out a new C-peptide test for type 1 diabetes that could help patients monitor their insulin levels with greater accuracy. The test provides information about the amount of insulin a patient has in their body, which can help determine whether they can reduce or stop taking their insulin injections.

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STAT News

APRIL 5, 2023

Researchers grouped pregnant women based on specific metabolic traits and found that insulin resistance was associated with the highest risk, compared with other traits such as high cholesterol and triglycerides, according to a study published in JAMA Network Open on Tuesday.

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