Medical Xpress

NOVEMBER 8, 2022

Researchers at the University of Maryland School of Medicine's (UMSOM) Center for Precision Disease Modeling identified how a specific protein in SARS-CoV-2, the virus responsible for COVID-19, damages heart tissue. They then used a drug to reverse the toxic effects of that protein on the heart.

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Protein Medicine Drugs Research 98

XTalks

MARCH 31, 2023

BMS researchers on the mission will study the crystallization of an assortment of their biologics medicines in microgravity. By growing high quality crystal structures of protein-based therapeutics under microgravity, researchers can gain better insights into their complex structures and stability.

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Protein Research Development Manufacturing 97

Medical Xpress

DECEMBER 5, 2022

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

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Protein Genetic Engineering Research Engineer 75

Scienmag

JUNE 30, 2021

Credit: Copyright Joslin Diabetes Center Elevated levels of three specific circulating proteins are associated with protection against kidney failure in diabetes, according to research from the Joslin Diabetes Center that will be published 30th June in Science Translational Medicine.

Protein 85

Protein Medicine Research 85

Scienmag

MARCH 4, 2022

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical “off switches” that silence them. Researchers from the University of Washington School of Medicine in Seattle describe this finding in the journal Cell Reports.

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Protein Gene Medicine Research 83

Scienmag

JUNE 9, 2021

Researchers identified the protein responsible for cancer’s aggressiveness Credit: Dorothy Kozlowski/UGA Prostate cancer is the second most common cancer among men, according to the American Cancer Society. But new research from the University of Georgia has identified a protein that appears to prevent the […].

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Protein Research Medicine 95

Scienmag

DECEMBER 23, 2021

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health.

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Protein Scientist Research Medicine 92

Pharmaceutical Technology

SEPTEMBER 14, 2022

API peptides and proteins-based drugs have gained much attention in the past decade. Discover the top API protein and peptide companies in contract marketing. Technologies in the delivery of peptides and proteins. They are promising therapeutics for the treatment of a variety of metabolic and oncological disorders.

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Protein Marketing Manufacturing Reagent 100

Pharmaceutical Technology

AUGUST 17, 2022

In the last 20 years, this is the biggest buzz in the vaccine market for Lyme disease,” said Yale School of Medicine associate professor Sukanya Narasimhan, PhD, about the Phase III VLA15 trial. However, advances in research allowed for the identification of outer surface protein A (OspA) of the bacteria as a target for vaccines.

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Vaccination Vaccine Bacteria Protein 299

Scienmag

APRIL 30, 2021

Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease Credit: Salk Institute LA JOLLA–(April 30, 2021) Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells.

Protein 97

Protein Scientist Research Medicine 97

XTalks

DECEMBER 10, 2024

Rilzabrutinib works by targeting BTK, a protein involved in immune cell communication. By inhibiting this protein, the drug disrupts pathways that contribute to platelet destruction and insufficient production. percent platelet response in a study published in The New England Journal of Medicine.

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Trials Protein Clinical Development Drugs 104

XTalks

DECEMBER 12, 2023

Plasma medicine is a critical and specialized field within healthcare, centering on the use of human plasma for the development and administration of life-saving treatments. Human plasma, the clear, liquid portion of blood, is composed of water, electrolytes, nutrients and crucial proteins such as antibodies, clotting factors and albumin.

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Medicine Recombinant Antibody Protein Antibody 111

Scienmag

JUNE 10, 2022

PHILADELPHIA — A stress protein that is overactive in many types of tumor cells also has a key role in tumor-supporting cells called fibroblasts, and may be a good target for future cancer treatments, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

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Protein Medicine Drugs Research 83

Medical Xpress

DECEMBER 21, 2022

A team at Canada's Lawson Health Research Institute has discovered unique patterns of blood plasma proteins in critically ill patients that may help develop a more personalized approach to treating severe COVID-19. Their work is published in the Journal of Cellular and Molecular Medicine.

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Protein Research Medicine Development 68

pharmaphorum

SEPTEMBER 14, 2020

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. At that time, we thought this would be the holy grail for medicine. Now, however, the field is changing with respect to genomic medicine.

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Genome Genomics Medicine Gene 119

Scienmag

OCTOBER 29, 2020

First study to show SARS-CoV-2 spike proteins disrupt the blood-brain barrier, potentially raising risk of neurological damage in COVID-19 patients Credit: Lewis Katz School of Medicine at Temple University (Philadelphia, PA) – Like a key, SARS-CoV-2 – the virus that causes coronavirus disease 2019 (COVID-19) – attaches to specific (..)

Protein 75

Protein Research Medicine 75

Scienmag

JUNE 29, 2022

In a study of eye fluid from 38 patients, Johns Hopkins Medicine researchers say they have found that levels of a specific protein appears to help accurately predict whether people with the wet form of age-related macular degeneration may need lifelong, frequent eye injections to preserve vision or if they can be safely weaned off […].

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Protein Medicine Research 80

Medical Xpress

JANUARY 2, 2023

Studying mice, researchers at Washington University School of Medicine in St. Louis have found that proteins made by stem cells that regenerate the cornea may be new targets for treating and preventing such injuries.

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Protein Medicine Research Genetics 145

Pharmaceutical Technology

MAY 15, 2023

Chinese biotech company LaNova Medicines and AstraZeneca have entered an exclusive licence deal for La Nova’s LM-305. AstraZeneca will receive an exclusive global licence for LM-305’s research, development and commercialisation. We’re excited to reach this agreement with AstraZeneca.

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Medicine Antibody Development Drugs 130

Scienmag

NOVEMBER 16, 2021

Research led by Boston Children’s Hospital, published today in Science Translational Medicine, describes a protein-based vaccine, […].

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Protein Vaccination Vaccine Immune Response 84

Scienmag

MAY 11, 2021

The researchers have demonstrated that silencing or inhibiting the activity of these proteins completely reverses the aortic disease in a mouse model of Marfan Syndrome Credit: CNIC Scientists at the Centro Nacional de Investigaciones Cardiovasculares Centro de Biología Molecular Severo Ochoa (CBM-CSIC-UAM) have discovered that the nitric oxide (NO) (..)

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Protein Scientist Research Cardiology 96

pharmaphorum

FEBRUARY 16, 2021

Medical charity Alzheimer’s Research UK has teamed up with artificial intelligence specialist Exscientia to find new drug treatments for the devastating neurodegenerative disease. . It reckons its use of AI and machine learning can trim years off the current 12- to 15-year cycle from early research to marketed product.

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Research Drugs Protein Development 119

Scienmag

MARCH 29, 2021

– New research led by scientists at Washington State University has found that a protein known as GBP5 appears to play a key role in suppressing inflammation in rheumatoid arthritis, a potentially debilitating disease in which the immune system mistakenly attacks the […].

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Protein Scientist Research Allergies 88

Scienmag

MARCH 25, 2021

This study will aid the understanding of, and future research on, inflammatory bowel disease, which afflicts about 1.6 – Researchers have found an unexpected synergy between a T-cell stimulatory protein — the ICOS ligand — and interleukin-10, an immunoregulatory cytokine, to prevent inflammatory bowel disease in mice.

Protein 91

Protein Research Allergies Medicine 91

Scienmag

MAY 14, 2021

Approach opens a new avenue to study the biology of acute leukemia and for the development of new drugs Credit: Grembecka / Cierpicki Labs The protein made by the ASH1L gene plays a key role in the development of acute leukemia, along with other diseases.

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Protein Development Research Gene 70

Medical Xpress

APRIL 5, 2023

A study by Indiana University School of Medicine researchers sheds new light on the development and treatment of a rare form of muscular dystrophy. The study's findings were recently published in Nature Communications.

Protein 75

Protein Research Medicine Development 75

Scienmag

MARCH 26, 2021

Discovery opens door to testing more effective drugs for treating COVID-19 patients University of Maryland School of Medicine (UMSOM) researchers have identified the most toxic proteins made by SARS-COV-2–the virus that causes COVID-19 – and then used an FDA-approved cancer drug to blunt the viral protein’s detrimental effects.

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Protein FDA Approval Drugs Medicine 71

Scienmag

APRIL 23, 2021

The protein, fast skeletal myosin binding […].

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Protein Research Medicine 78

Scienmag

JULY 2, 2021

Studies using human cell lines and tumors grown in mice provide early evidence that inhibiting RNA-binding proteins, a previously overlooked family of molecules, might provide a new approach for treating some cancers Credit: UC San Diego Health Sciences In cancer research, it’s a common goal to find something about cancer cells — some sort (..)

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RNA Protein Drugs Research 87

Medical Xpress

NOVEMBER 10, 2022

Scientists have used a proteomics approach to identify a three-protein signature in the blood that can improve detection of isolated impaired glucose tolerance, a form of prediabetes. The research, led by scientists from the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge, U.K.,

Protein 75

Protein Scientist Medicine Research 75

Worldwide Clinical Trials

AUGUST 14, 2024

They play a crucial role in tailoring hematology oncology therapeutic strategies to individual patients and have transformed personalized medicine in oncology. Protein-based Biomarkers : Include proteins found in blood, tissues, or other bodily fluids that can indicate disease presence or progression.

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Genetics Protein Gene Genotype 195

Worldwide Clinical Trials

APRIL 15, 2025

Despite their clinical heterogeneity, these diseases often share overlapping pathological mechanisms, including protein misfolding and aggregation, synaptic dysfunction, neuroinflammation, and axonal degeneration. Alzheimers Disease AD is a progressive neurodegenerative disorder characterized by cognitive decline and memory impairment.

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Clinical Trials Clinical Trials Trials Protein 100

Scienmag

OCTOBER 21, 2020

Computational and experimental research by joint UC Berkeley-ITU team seeks unknown vulnerabilities of coronavirus Credit: Ahmet Yildiz, University of California, Berkeleky; Mert Gur, Istanbul Technical University The virus wreaking havoc on our lives is an efficient infection machine.

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Protein Genome Genomics Research 76

Medical Xpress

JANUARY 5, 2023

Researchers at Baylor College of Medicine have found more evidence that dry fasting (fasting without food or liquid intake) from dawn to dusk can play an important role in overall health.

Protein 123

Protein Medicine Research 123

Pharmaceutical Technology

MARCH 10, 2023

Personalised medicines will also be developed at the centre. In the past, researchers have often had to seek help from outside the UK, thus delaying clinical trials and patient access. Operations at the CBC will focus on building plasmids , viral vectors and recombinant proteins for the production of cell and gene therapies.

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Gene Therapy Manufacturing Gene Clinical Trials 264

XTalks

JANUARY 21, 2025

The approval makes Datroway AstraZenecas eighth new medicine since 2020, the first US approval for Daiichi Sankyo and AstraZenecas TROP2-directed ADC and the second based on their proprietary DXd technology. The FDA approval sent Daiichi Sankyos shares soaring by 8.7% to 4,437 yen, reflecting investor confidence.

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Antibody FDA Approval HR Trials 105

Scienmag

JULY 20, 2021

New research published in the Journal of Leukocyte Biology reveals that certain protein markers may indicate which patients have stable forms of CLL and which have more aggressive types. Identifying these proteins may not only help determine patients’ prognoses but also point […].

Protein 75

Protein Scientist Research Medicine 75