XTalks

MAY 29, 2024

The top ten pharma companies in 2023 by revenue accounted for about 35 percent of the market value, with total earnings of $559.5 The top big pharma players have remained relatively consistent in their market positions over the past several years. Here is a look at the top ten pharma companies in 2024 based on 2023 revenue.

Pharma Companies 52

Pharma Companies Sales FDA Approval Vaccine 52

pharmaphorum

AUGUST 18, 2020

This is a question that a consortium of European pharma companies hopes to answer as it aims to rapidly develop new therapies to combat the pandemic. Could AI prevent future pandemics by developing an armoury of drugs that work against all coronaviruses? But also included in the 77.7

Protein 121

Protein Pharma Companies RNA Drugs 121

pharmaphorum

SEPTEMBER 2, 2020

But many patients still do not respond to therapies such as Merck & Co’s anti PD-1 therapy Keytruda (pembrolizumab), or go on to develop progressive disease, and pharma companies are looking for new second-line therapies.

Trials 111

Trials RNA Pharma Companies Clinical Trials 111

pharmaphorum

JANUARY 6, 2021

Pharma companies are always talking about moving ‘beyond the pill’, and Pfizer’s new brand identity embodies that – it’s decades old pill-like logo has been replaced with a DNA double helix that it says reflects its commitment to breakthrough science. — Tinglong Dai (@TinglongDai) January 5, 2021.

DNA 116

DNA Branding Vaccine Vaccination 116

pharmaphorum

JANUARY 12, 2021

US biotech Atalanta Therapeutics has come out of stealth mode backed with $110m from Biogen and Roche, who have also signed separate partnerships to develop new therapies for neurological diseases using RNA interference (RNAi) technology.

RNA 95

RNA Production Development Pharma Companies 95

XTalks

AUGUST 18, 2020

An important feature of the test that contributes to its reduced cost is the fact that sample processing does not require a separate nucleic acid (RNA) extraction step. This is significant because shortages of RNA extraction kits have been a recurrent issue since the beginning of the pandemic.

FDA Approval 90

FDA Approval Reagent RNA Genome 90

pharmaphorum

AUGUST 23, 2022

Explaining why Ampligen may prove effective, the spokesperson said, “Ampligen is a selective TLR3 agonist which — to put it very simply — works to activate immune cells, shut down protein replication and chew-up viral RNA, all of which can help stop the virus from replicating and hopefully even eradicate it.

Vaccine 134

Vaccine Vaccination Development Trials 134

pharmaphorum

DECEMBER 7, 2021

The deal – which is weighted heavily towards neuroscience with just one cancer programme covered – is the second between Recursion and a big pharma company in the space of two days, coming on the heels of a smaller alliance with Bayer that will look for new fibrosis drugs.

Drugs 59

Drugs RNA Pharma Companies Protein 59

XTalks

JANUARY 3, 2025

XTALKS WEBINAR: Environmental Sustainability and the Supply of Medicines for Clinical Trials Live and On-Demand: Thursday, January 16, 2025, at 10am EST (4pm CET/EU-Central) Register for this free webinar to learn how major pharma companies are working towards environmental sustainability and reducing their environmental impact.

FDA Approval 59

FDA Approval Drugs Clinical Trials Clinical Trials 59

pharmaphorum

DECEMBER 21, 2020

Compared with many of the established names in pharma these companies are young upstarts but they have managed to achieve what other big names in the industry have failed to do and harness the power of mRNA to make medicine. He told pharmaphorum: “They are very good doctors, scientists and entrepreneurs.

Vaccination 111

Vaccination Vaccine Doctors Doctor 111

pharmaphorum

MARCH 11, 2022

However, the financial success that has been delivered to certain companies working on vaccine development has emerged after a long period where investing in the space had become increasingly unpopular among the larger pharma companies.

Vaccination 81

Vaccination Vaccine Development Manufacturing 81

pharmaphorum

APRIL 28, 2022

Despite the inherent difficulties, major pharma companies do take aim at rare diseases, usually with dedicated units focusing on clusters of rare diseases that afflict the same part of the body. How big pharma tackles rare diseases. It’s a different business model, if you will,” Miquel said. “So So that is the trick.

Pharma Companies 59

Pharma Companies Branding Development Marketing 59

XTalks

DECEMBER 13, 2023

These companies were identified through The Americas’ Fastest-Growing Companies 2023 list by the Financial Times. Notably, Twist Bioscience continues to enhance its NGS portfolio by introducing a new RNA sequencing portfolio, catering to the extensive research market.

Genetics 111

Genetics Vaccination Vaccine DNA 111

pharmaphorum

NOVEMBER 23, 2021

The bolt-on deal comes – which includes an upfront payment of $120 million and up to $910 million in milestones – covers rights to ARO-HSD, Arrowhead’s RNA interference drug targeting an enzyme called HSD17B13 that seems to contribute to the pathology of NASH and other liver diseases.

Sales 52

Sales Drugs Trials RNA 52

Delveinsight

JANUARY 8, 2021

HDV is nothing but a defective RNA virus, a satellite of the helper Hepatitis B virus (HBV) that needs the HBsAg of the hepatitis B virus (HBV) for virion assembly, release, and transmission. HDV infection can be acute or lead to chronic, long-term illness.

Marketing 52

Marketing RNA Development Pharma Companies 52

pharmaphorum

DECEMBER 23, 2020

Pharma companies have also made headway in rare diseases as several pipeline projects came to fruition. It was the third approval from Alnylam’s pipeline of RNA interference therapeutics to make it to market. Rare disease progress.

Marketing 97

Marketing Gene Gene Silencing Drugs 97

Delveinsight

FEBRUARY 8, 2021

The major factors shaping the market outlook include prevalence, monopoly of a pharma company, diagnostics and screening methodologies, entry of other market players in the Cystic Fibrosis market domain, as well as restraints. and Verona Pharma’s RPL 554.

Marketing 52

Marketing Development Production Drugs 52

Delveinsight

AUGUST 6, 2020

The present hATTR treatment market constitutes compounds that stabilize the TTR tetramers, a TTR-directed small interfering RNA, and a TTR-directed antisense oligonucleotide, along with supportive therapies. The past years have witnessed a shift from off-label and symptomatic therapies to approved TTR stabilizers and gene-silencing therapies.

Protein 52

Protein Gene Silencing Marketing Gene 52

The Pharma Data

MAY 13, 2021

Unfortunately, I learned the hard way that the “Big Pharma” companies don’t care about their patients. Stimulates DNA and RNA synthesis. Why do doctors prescribe drugs which are so powerful they require a second set of medication just to deal with the side effects! It’s all about the bottom line, at any cost.

Production 52

Production Pharmacy Doctors Doctor 52

Roots Analysis

AUGUST 13, 2024

Messenger ribonucleic acid (mRNA) is a type of single-stranded ribonucleic acid (RNA), which helps in transferring genetic information in order to produce proteins. The success of mRNA-based therapeutics and vaccines has increased the research activity in novel / next generation RNA therapeutics market.

Vaccination 40

Vaccination Vaccine Manufacturing Protein 40

Pharmaceutical Technology

DECEMBER 19, 2022

Pierre Socha, partner at Amadeus Capital Partners, London, UK, predicts that larger pharmaceutical companies may have similar interests. Most pharmas will buy biotech companies or smaller pharma groups for the quality of their clinical assets and the drugs on their developments,” he says.

Life Science 173

Life Science Manufacturing Medicine Production 173

XTalks

JANUARY 6, 2025

From leveraging artificial intelligence (AI) to streamline diagnostics and treatments to exploring the untapped potential of RNA-based therapeutics, biotechnology is shaping the future of healthcare and beyond. As of January 31, 2024, approximately 131 unique RNA-based therapies are in clinical development across various therapeutic areas.

Gene Therapy 111

Gene Therapy RNA Gene Editing Gene 111

XTalks

FEBRUARY 11, 2025

Gene therapy has shown promise in treating cancers that are particularly difficult to manage such as neuroblastoma and Wilms tumor using CAR-T cell therapy, CRISPR-Cas9 gene editing and RNA-based interventions to target genetic drivers of disease.

Gene Therapy 66

Gene Therapy Clinical Trials Clinical Trials Trials 66

XTalks

FEBRUARY 11, 2025

billion in total sales for 2022, the most ever reported by any pharma company in a single year. of patients on Genvoya and 80% of those on Stribild achieved HIV-1 RNA levels below 50 copies/mL. of those on Stribild achieved HIV-1 RNA levels below 20 copies/mL, which was a secondary endpoint. At Week 144, 84.2%

Sales 66

Sales FDA Approval Vaccination Vaccine 66