Medical Xpress

APRIL 21, 2023

A new publication released today in The EMBO Journal identified a key protein in the molecular mechanism triggering neurogenesis in the hippocampus. They found that tight regulation of Yap1 activity is essential as dysregulation can cause tissue disruption seen in the early stages of brain cancer.

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Pharmaceutical Technology

MAY 9, 2023

The companies will use the natural product discovery capabilities of Ginkgo Bioworks to expedite the discovery and development of new therapeutic molecules to address diseases with high unmet patient needs.

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Scienmag

JULY 7, 2022

A collaboration including researchers from Kobe University, University of Tokyo and Tohoku University has successfully identified and disrupted genes in the yeast Pichia pastoris (1) in order to increase its secretory production of useful proteins (2).

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XTalks

APRIL 26, 2022

California-based startup Air Protein developed an alt meat called Air Meat, which is made using microbes that turn recycled carbon dioxide (CO2) into protein. Described by the company as “the meat of tomorrow,” Air Meat was designed to replicate the flavor and texture of real meat products like chicken, pork, steak and seafood.

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XTalks

MARCH 31, 2023

BMS researchers on the mission will study the crystallization of an assortment of their biologics medicines in microgravity. By growing high quality crystal structures of protein-based therapeutics under microgravity, researchers can gain better insights into their complex structures and stability.

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Pharmaceutical Technology

SEPTEMBER 14, 2022

API peptides and proteins-based drugs have gained much attention in the past decade. Peptide API products have become popular due to their proven pharmacological value and favourable safety profiles. Discover the top API protein and peptide companies in contract marketing. Technologies in the delivery of peptides and proteins.

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Pharmaceutical Technology

APRIL 21, 2023

In May 2022, they signed a research partnership and exclusive option licence agreement for the development of antibodies to reduce tumour microenvironment-mediated immunosuppression. The companies signed another research collaboration agreement for multi-target antibody discovery in January 2023.

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Medical Xpress

FEBRUARY 22, 2023

Medicines that are based on mRNAs and proteins—particularly vaccines and antibodies—are time-intensive and costly to make. The challenge is in producing the necessary mRNAs and proteins in large enough amounts at low cost.

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Pharmaceutical Technology

APRIL 6, 2023

Biotheryx and Incyte have signed an agreement for identifying and developing targeted protein degraders for historically undruggable oncology targets. Incyte will pay a $7m technology access fee to Biotheryx for the initial target and potential research, and development funding of up to an additional $6m for costs related to the partnership.

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XTalks

DECEMBER 10, 2024

Rilzabrutinib joins a wave of innovative ITP therapies , including thrombopoietin-receptor agonists like eltrombopag and romiplostim, which boost platelet production. Rilzabrutinib works by targeting BTK, a protein involved in immune cell communication.

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XTalks

JULY 26, 2021

But several researchers and experts have brought to light some food safety concerns of plant-based meat, and why it must be treated differently than that of animal protein. Traditional meat production faces a wide array of safety concerns, from slaughterhouse sanitation to foodborne illnesses and much more. Ultra-Processed.

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XTalks

FEBRUARY 25, 2022

EverGrain Ingredients, a barley protein and fiber solutions company, recently received certification from the Upcycled Food Association (UFA) for its entire portfolio of products. The brand saw a unique opportunity to extract the excess barley to meet the global demand for sustainable, plant-based products. Barley Milk.

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Drug Discovery World podcast

JANUARY 9, 2025

This is the latest episode of the free DDW narrated podcast, titled Where are the global breakthroughs, opportunities and developments in cancer research?, I spoke with him about how AstraZeneca is innovating to displace chemotherapy and research areas of significance. appeared first on Drug Discovery World (DDW).

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XTalks

JANUARY 29, 2021

Oncology products monopolise the list of best-selling drugs. Several oncology products now have “blockbuster” status where sales exceed $1 billion annually. This is relevant for clinical trials as more regulators require evidence of efficacy in comparison to the standard of care, which is likely to be one of the blockbuster products.

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Pharmaceutical Technology

JANUARY 16, 2023

Ono Pharmaceutical and Monash University have entered an option and research collaboration for the discovery and development of antibodies that target G protein-coupled receptors (GPCRs). The post Ono Pharmaceutical enters research deal with Monash University appeared first on Pharmaceutical Technology.

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Scienmag

JANUARY 7, 2022

The research by the Future Sustainable Food Systems research group at the University of Helsinki together with VTT Technical Research Centre of Finland shows that fungus-produced ovalbumin could have the potential to mitigate part of the environmental burden associated with chicken egg white powder.

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World of DTC Marketing

DECEMBER 29, 2020

First, a novel approach was used that didn’t require traditional vaccine production in cell cultures or eggs. Once introduced into the human body, the protein-making machinery uses this genetic material in our cells to churn out the coronavirus “spike protein,” triggering an immune response.

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Pharmaceutical Technology

APRIL 11, 2023

Drug discovery company Veneno Technologies has signed a joint research agreement with Japanese pharmaceutical company Astellas Pharma. Veneno will carry out a programme to generate functional peptides (DRPs) for G protein-coupled receptors (GPCRs), which will be targeted by Astellas.

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Pharmaceutical Technology

MARCH 10, 2023

In an email to Pharmaceutical Technology , an NHSBT spokesperson said the centre will “support early phase clinical trials and preclinical work, providing a route to eventual commercial scale production”. The NHSBT representative explained that a lack of manufacturing spaces led to delays in production slots for many gene therapy developers.

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Medical Xpress

JANUARY 20, 2023

This process is regulated by a family of signaling proteins called sirtuins. A recent study by researchers from Kumamoto University reveals the mechanism through which the protein sirtuin 7 suppresses thermogenesis in mice. Mammals convert the energy stored in adipose (fat) tissue into heat via a process known as thermogenesis.

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XTalks

JUNE 8, 2023

Ever After Foods’ unique breakthrough lies in its proprietary bioreactor setup, which has the potential to tackle the central challenge of escalating cultivated meat production. Recent research suggests that cultivated meat is more sustainable than traditional animal products, especially when coupled with renewable energy use.

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Camargo

NOVEMBER 29, 2021

The development of biological products (or biologics) represents a major advancement in modern medicine, enabling the treatment of patients with many illnesses where no other therapeutics were previously available. Definition of Biologic Products. These products can be derived from humans, animals, or microorganisms with biotechnology.

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Pharmaceutical Technology

DECEMBER 23, 2022

As per the prior and expanded agreements, ProQR is entitled to get research, development and commercialisation milestone payments totalling up to nearly $3.75bn, apart from tiered royalty payments on sales of products. The company can also choose to grant ProQR access to its delivery technology for the fully owned pipeline.

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pharmaphorum

FEBRUARY 16, 2021

Medical charity Alzheimer’s Research UK has teamed up with artificial intelligence specialist Exscientia to find new drug treatments for the devastating neurodegenerative disease. . It reckons its use of AI and machine learning can trim years off the current 12- to 15-year cycle from early research to marketed product.

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Medical Xpress

MAY 9, 2023

Researchers at the CNIO (Spanish National Cancer Research Center) have discovered that one of the causes for the rare tumor pheochromocytoma-paraganglioma is the interruption of a very specific step in the production of some proteins, called succinylation.

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XTalks

JUNE 10, 2021

Amazon’s Launchpad program empowers and accelerates start-up businesses that will sell their products amazon.com. Until now, no plant-based products could match what the sports nutrition category was doing. ” Related: RXBAR Introduces its First Plant-Based Protein Bar. Additionally, GNC placed an initial $3.4

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Pharmaceutical Technology

SEPTEMBER 2, 2022

Forma focuses on researching, developing and marketing new therapies for patients with sickle cell disease (SCD), rare hematologic diseases and cancers. A group of ailments, haemoglobinopathies is associated with an irregular production or structure of the haemoglobin protein in the red blood cells.

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Pharmaceutical Technology

NOVEMBER 14, 2022

binding antibody, a cell-surface protein which is greatly expressed in ovarian cancer, as well as the maytansinoid payload DM4. In February, the company signed a licencing agreement under which Eli Lilly and Company obtained exclusive rights to conduct the research, development and marketing of ADCs. The ADC comprises an FR?-binding

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XTalks

FEBRUARY 29, 2024

Dual-function fusion proteins represent a cutting-edge approach in biopharmaceutical research, offering a promising avenue for the development of novel therapeutics in the treatment of complex diseases such as cancer and autoimmune disorders. My initial exposure to medicine came through bench research.

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Pharmaceutical Technology

JANUARY 23, 2023

The introduction of new first-in-class biological therapies will further increase therapy options for SLE and LN patients, and it remains to be seen if any of these products will have superior efficacy and safety profiles to currently available Benlysta, Rituxan, Lupkynis and Saphnelo.

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Medical Xpress

FEBRUARY 22, 2023

The results are reported in an article published in the journal Probiotics and Antimicrobial Proteins. The authors are researchers at the University of São Paulo (USP) and the Federal University of Minas Gerais (UFMG). The yeast strain used in the study was Saccharomyces cerevisiae UFMG A-905.

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Production Protein Research 98

XTalks

APRIL 13, 2021

Now, thanks to a study funded by the National Institutes of Health Intramural Research Program, scientists have discovered that ?-synuclein, synuclein, a protein involved in the formation of amyloid deposits in the brain characteristic of Parkinson’s disease and other neurodegenerative disorders, is also implicated in melanoma.

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pharmaphorum

FEBRUARY 14, 2022

A recent report has found that R&D productivity rose vertiginously during 2021, but how much of this was organic and how much can be attributed to the pandemic? The pandemic also saw a reduction in the overall development cycle of a product, which has been growing in recent years. In 2020, the development cycle averaged 7.14

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Pharmaceutical Technology

FEBRUARY 3, 2023

Since HIV integrates with the DNA, eliminating the virus from the body is very difficult, explains David Montefiori, PhD, director of the Laboratory for AIDS Vaccine Research and Development at Duke University in Durham, North Carolina. But others in the research space are now testing out other concepts that have been largely theoretical.

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XTalks

JULY 19, 2022

The two-dose protein-based, adjuvanted vaccine has been authorized for use in adults 18 years of age and older for the prevention of COVID-19 caused by SARS-CoV-2. Nevertheless, 77 percent of those polled said that even if a protein-based COVID shot were authorized in the US, they still would not get it.

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Pharmaceutical Technology

NOVEMBER 1, 2022

However, according to new research by the University of Cincinnati, amyloid plaques may not be the major cause of AD as previously thought—so are they the best target? ABPP Inhibitors lead by a significant margin, having 38% more drugs in development than the next leading MoA, microtubule-associated protein tau (MAPT) inhibitors.

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Medical Xpress

JANUARY 4, 2023

In a new study by researchers from Mass General Brigham's founding members, Brigham and Women's Hospital and Massachusetts General Hospital, a team extensively investigated the immune response of 16 adolescents and young adults who developed myocarditis after receipt of the COVID mRNA vaccine. Their results are published in Circulation.

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