Scienmag

DECEMBER 8, 2020

Credit: Kim Ratliff, Production Coordinator, Augusta University A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

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Protein DNA Scientist Production 76

Pharmaceutical Technology

DECEMBER 7, 2022

Researchers are also investigating blood-based biomarkers to bolster efforts to find Alzheimer’s drugs that go beyond targeting the amyloid protein, so new targets can be tackled, potentially widening the pool of patients who may respond to a therapy. Developing treatment biomarkers and diagnostic biomarkers may help achieve these goals.

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Scienmag

JULY 6, 2021

Credit: Lorna Dougan/Phospho Animations Scientists at the University of Leeds have developed an approach that could help in the design of a new generation of synthetic biomaterials made from proteins. But one […].

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Development Protein Scientist Production 95

Scienmag

NOVEMBER 1, 2020

Scientists from an international group led by the RIKEN Center for Integrative Medical Sciences and Yokohama City University have discovered that a pair of proteins play a key role in allowing an important type of functional non-coding RNA, known as SINEUPs, to act to promote their target messenger RNA.SINEUPs are a recently discovered type of […]. (..)

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Protein Production RNA Research 45

XTalks

NOVEMBER 8, 2024

Top Hospital-Based Healthcare Innovations Google DeepMind AlphaFold 3: Rendering Molecules in HD Drug discovery often hinges on predicting how proteins interact with each other. The free AlphaFold Server is available to scientists globally to access high-definition molecular predictions.

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Doctors Doctor Protein Nurses 104

Scienmag

MARCH 9, 2022

A team led by scientists at the University of Birmingham has come a step closer to uncovering the purpose of a distinctive set of modifications found at the beginning of messenger RNA which have long remained a fundamental mystery in molecular biology. Messenger RNAs (mRNAs) are vital for protein production.

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RNA Research Protein Scientist 80

Pharmaceutical Technology

APRIL 26, 2023

Qalsody is an antisense oligonucleotide (ASO) that has been designed for binding to SOD1 mRNA to reduce the production of SOD1 protein. It is reported to be the first treatment targeting a genetic cause of ALS to receive approval.

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Genetics Protein Trials Gene 130

Scienmag

DECEMBER 6, 2020

Credit: Kim Ratliff, Production Coordinator, Augusta University How well women with cervical cancer respond to treatment and survive correlates with the level of 10 proteins in their blood that also are associated with a “zombie” cell state called senescence, Medical College of Georgia scientists report.

Protein 71

Protein Scientist Production Medicine 71

Scienmag

NOVEMBER 20, 2020

Scientists at Goethe University within the international consortium COVID19-NMR refine previous 2D models The genetic code of the SARS-CoV2 virus is exactly 29,902 characters long, strung through a long RNA molecule. It contains the information for the production of 27 proteins.

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Genome Genomics RNA Protein 70

XTalks

JULY 8, 2021

Its products are derived from a fermented volcanic microbe found at Yellowstone National Park. . Along with a team of scientists, Kozubel fermented the microbe into a protein-rich substance and dubbed it “Fy.” Along with a team of scientists, Kozubel fermented the microbe into a protein-rich substance and dubbed it “Fy.”

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Protein Production Branding Marketing 98

The Pharma Data

MARCH 23, 2022

Polymerase is a viral protein that directs how Ebola virus replicates its genome as it infects new hosts. Now scientists at La Jolla Institute for Immunology (LJI) and Scripps Research have found a promising strategy for stopping Ebola virus polymerase. and University of Texas Medical Branch (UTMB) Professor Alexander Bukreyev, Ph.D.

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Protein Genome Genomics Research 52

The Pharma Data

SEPTEMBER 30, 2021

The settlement of circulating tumor cells during a distant organ is promoted by factors whose production is induced by the first tumor itself. during this way, the scientists were ready to observe the event of metastases within the absence of the first tumor.

Protein 52

Protein Scientist Antibody Research 52

XTalks

APRIL 13, 2021

Now, thanks to a study funded by the National Institutes of Health Intramural Research Program, scientists have discovered that ?-synuclein, synuclein, a protein involved in the formation of amyloid deposits in the brain characteristic of Parkinson’s disease and other neurodegenerative disorders, is also implicated in melanoma.

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Research Protein In-Vitro Scientist 98

Pharmaceutical Technology

JULY 7, 2022

But scientists have struggled to find effective treatments for many of these diseases since the dawn of modern medicine. Often referred to as a type of gene-modified cell therapy, CAR-T cell therapies involve genetically modifying a patient’s own T cells to produce a protein that enables them to identify and kill cancer cells.

Gene Therapy 245

Gene Therapy Gene Medicine Genetics 245

The Pharma Data

DECEMBER 3, 2020

New Tau Protein is Abnormal in Very Early Alzheimer’s Disease. Investigators with the University of Gothenburg identified new forms of tau protein that become abnormal in the very early stages of Alzheimer’s disease, even before the development of cognitive problems. “The Every week there are numerous scientific studies published.

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Protein Research Gene Regulation 52

XTalks

AUGUST 30, 2021

While these climate change-induced factors tend to make farming difficult and disrupt food distribution, Dubai’s International Center of Biosaline Agriculture (ICBA) is creating solutions to boost local food production in the driest and hottest conditions. Another lesser-known crop called Salicornia is also thriving in the desert.

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Production Protein Scientist Research 125

Pharmaceutical Technology

APRIL 28, 2023

Its scope includes Syngene providing integrated drug discovery and development solutions in discovery chemistry and biology, peptide chemistry, antibody and protein reagents, pharmacokinetics and drug metabolism, and pharmaceutical development. until 2026. Profile Syngene International Ltd.

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Pharmaceutical Technology

FEBRUARY 22, 2023

Both drugs are monoclonal antibodies that inhibit the protein PCSK9. But in this case, Amgen has a fully finished product, he adds. But other experts say that Amgen’s win could discourage scientists and competitors from making future innovations, since these broad claims let patentees monopolise the area.

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Antibody Drugs Protein Sales 262

XTalks

MAY 5, 2021

Plant-based meat has come a long way since food tech got involved, but will any chef, scientist or a hybrid of the two be able to create the perfect plant-based marbled steak? Juicy Marbles uses a patent-pending machine called the Meat-o-Matic Reverse Grinder 9000 to layer soy protein into linear fibers of the steak.

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Containment Production Protein Branding 105

Scienmag

JUNE 29, 2021

Scientists at Berkeley Lab, UC Berkeley design 3D-grown material that could speed up production of new technologies for smart buildings and robotics Credit: Berkeley Lab Crystallization is one of the most fundamental processes found in nature – and it’s what gives minerals, gems, metals, and even proteins their structure.

Protein 57

Protein Scientist Production Engineer 57

pharmaphorum

JULY 14, 2021

Pasadena, California-based Protomer is working on proteins that can sense molecular activators in the body and only become activated when needed. It was also responsible for the first recombinant insulin product – Humulin – which launched in 1982 and remains on sale. Alborz Mahdavi.

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Insulin Protein Production Development 98

XTalks

AUGUST 19, 2022

Once fermented, the cell-cultured cocoa nibs are ready to be turned into a variety of cell-based chocolate products. Scientists at the Zurich University of Applied Sciences (ZHAW) developed cell-based chocolate back in July 2021 to see what the future of food out of tanks might look like.

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Scientist Production Protein Development 98

XTalks

DECEMBER 10, 2020

Funded by EIT Food , the Digital Marketplace for Side Streams will help food companies upcycle waste to produce by-products by matching them with businesses that have an overabundance of food. The goal of the marketplace is to inspire more companies to consider ways they can reduce waste from food production.

Cosmetics 98

Cosmetics Production Protein Scientist 98

XTalks

NOVEMBER 8, 2021

Beans, soy, tofu, mushrooms and pea protein are some of the most common ingredients in meat analogues, but kelp could soon be added to that list. Aiming to solidify a prominent place in the booming plant-based meat market, AKUA came out with its first product in 2019 — Kelp Jerky. The global meat substitute market was valued at $4.51

Containment 98

Containment Protein Marketing Production 98

pharmaphorum

SEPTEMBER 14, 2020

A UK safety committee has concluded its investigations and recommended to the country’s Medicines and Healthcare products Regulatory Agency (MHRA) that trials are safe to resume. We will back our scientists to deliver an effective vaccine as soon as safely possible [link]. This pause shows we will always put safety first.

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Vaccination Vaccine Trials Protein 104

The Pharma Data

DECEMBER 1, 2020

The Single-Cell Intracellular Proteome chip provides a simple, integrated solution for monitoring simultaneous protein signaling networks that are missed by methods such as western blot, mass spectrometry, and flow cytometry. For more information about The Scientist ‘s 2020 Top 10 Innovations and the full list of winners, visit: [link].

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Scientist Protein Life Science Development 40

pharmaphorum

SEPTEMBER 17, 2020

The vaccine is based on a weakened virus that causes cold symptoms in chimpanzee, which causes an immune respone with genetic material coding for the spike protein found on the surface of the coronavirus. According to the World Health Organization, AZ’s vaccine is the most advanced in a list of 36 vaccines in clinical trials for COVID-19.

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Vaccination Vaccine Trials Medicine 105

The Pharma Data

OCTOBER 27, 2021

The neutralizing activity of the sera developed by the scientists has been proved to be high against the P.1 “By using the trimeric spike protein of SARS-COV-2 to immunize horses, a cocktail of purified IgG fragments (F(ab’)2) showing very high neutralizing activity was developed. 1 (Gamma) and P.2 2 variants. iScience, 2021.

Antibody 52

Antibody Protein Scientist Clinical Trials 52

XTalks

DECEMBER 12, 2023

Human plasma, the clear, liquid portion of blood, is composed of water, electrolytes, nutrients and crucial proteins such as antibodies, clotting factors and albumin. Patients have better quality of life thanks to many Grifols plasma-derived medicines that replace missing or deficient plasma proteins.

Medicine 111

Medicine Recombinant Antibody Protein Antibody 111

Pharmaceutical Technology

FEBRUARY 23, 2023

Quotient Sciences helps biotech and pharma customers in the development and optimization of drug products. Our chemists and formulation scientists review the properties of new drug candidates and “work their magic” to develop formulations that improve the exposure profile of the compound.

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Development Drugs Bioavailability In-Vivo 246

pharmaphorum

AUGUST 13, 2021

Six years ago, research scientist Inbal Zafir-Lavie tragically lost her 38-year-old sister Hava Zafir to colorectal cancer. A few years ago, Inbal co-founded the start-up GinaLife, where she currently leads a team developing technologies in the field of women’s health, with its first product focused on early detection of ovarian cancer.

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Clinical Trials Clinical Trials Production Research 105

XTalks

APRIL 14, 2021

Scientists used synthetic biology and computational protein design tools to develop an enzymatic process to transform red cabbage anthocyanins into their desired color. This process has been used in the food industry before, such as in cheese production, for example. How Are Synthetic Food Dyes Regulated?

Regulation 94

Regulation Production Branding Research 94

XTalks

JANUARY 28, 2021

Eat JUST, the food tech company that pioneered the plant-based egg movement, announced it will be debuting a new product under its JUST Egg line. The mung bean-based bites are derived from the same recipe as JUST Eggs, the liquid egg product that garnered massive success around the world.

Production 59

Production Protein Manufacturing Containment 59

pharmaphorum

APRIL 5, 2022

The technique uses artificial intelligence (AI) to analyse protein data harvested from tumour cells, using an algorithm trained by looking at changes to 52 proteins when they are exposed to a panel of targeted anticancer drugs. The post AI test could predict best cancer therapies for patients appeared first on.

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Protein Genome Genomics Genetic Analysis 67

XTalks

SEPTEMBER 8, 2020

Our experience in drug product fill/finish will enable timely manufacturing to make the vaccine available as soon as possible to advance bringing life-changing medicines to market.”. The genetic material contains SARS-CoV-2 spike protein. The Phase 3 trial is being implemented as part of Operation Warp Speed.

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Manufacturing Vaccination Vaccine Allergies 83

The Pharma Data

NOVEMBER 10, 2020

Herbert served as Vice President of Process Development & Engineering at Alkermes, where he led teams of up to 100 individuals in all aspects of drug product operations, including sterile process design, regulatory documentation, CDMO/CMO management, and clinical manufacturing. It’s a pleasure to welcome Paul to the Elektrofi team.

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Development Engineer Manufacturing Life Science 52

Cloudbyz

MARCH 5, 2024

The difference between biologics vs small molecules in pharma drug development In pharmaceutical drug development, biologics and small molecules represent two distinct categories of medicinal products, each with their own unique characteristics, development processes, and mechanisms of action.

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Development Drugs Immune Response Manufacturing 97