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Recurrent brain trauma may increase Alzheimer's risk

Medical Xpress

New research finds that the brains of otherwise healthy military personnel who are exposed to explosions show an abnormal brain accumulation of amyloid-beta protein—a protein that plays a role in the development of Alzheimer's disease. The results of the study were published today in Radiology.

Radiology 104
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Small glowing protein allows researchers to peer deeper into living tissues

Medical Xpress

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

Protein 75
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Research Roundup: UK Strain of COVID-19 and More

The Pharma Data

Researchers say, however, they have never seen a virus acquire more than a dozen mutations at once. Of the 17 mutations, eight are in the gene that encodes the spike protein. One is N501Y, which has been previously shown to increase how the spike protein binds to the ACE2 receptor. In research in South Africa in B.1.1.7,

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AstraZeneca’s COVID-19 vaccine; Type 1 diabetes research updates; FDA nod to Zebra’s X-ray modelling AI; UniQure/CSL haemophilia B gene therapy curbs bleeding in phase 3

Delveinsight

That disparity that startled the researchers running the trials has been the topic of debate since AstraZeneca shared the top-line data. Warding off Type 1 diabetes by aiming a T-cell protein. The protein is known as OCA-B. The efficacy of the 2,741-subject half-dose primer arm was 90%.

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AZD1222 US Phase III primary analysis confirms safety and efficacy

The Pharma Data

It uses a replication-deficient chimpanzee viral vector based on a weakened version of a common cold virus (adenovirus) that causes infections in chimpanzees and contains the genetic material of the SARS-CoV-2 virus spike protein. The Phase III D8110C00001 trial is part of this funding agreement. JPEO-CBRND.

Vaccine 52
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AZD1222 US Phase III trial met primary efficacy endpoint in preventing COVID-19 at interim analysis

The Pharma Data

It uses a replication-deficient chimpanzee viral vector based on a weakened version of a common cold virus (adenovirus) that causes infections in chimpanzees and contains the genetic material of the SARS-CoV-2 virus spike protein. The Phase III D8110C00001 trial is part of this funding agreement. JPEO-CBRND.

Trials 52
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Virus that causes COVID-19 can find alternate route to infect cells

The Pharma Data

Now, researchers at Washington University School of Medicine in St. The ability to use an alternative entry pathway opens up the possibility of evading COVID-19 antibodies or vaccines, but the researchers did not find evidence of such evasion. The study is published June 23 in Cell Reports. Ben Major, PhD, the Alan A. and Edith L.