Bio Pharma Dive

SEPTEMBER 20, 2023

Targeted protein degradation has emerged as one of the more competitive areas of pharmaceutical research in recent years as scientists develop new ways to reach difficult-to-drug targets.

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Drugs Protein Scientist Development 263

AuroBlog - Aurous Healthcare Clinical Trials blog

JULY 30, 2023

Key to this newly discovered process is GRP78, and it’s what’s known as a chaperone protein. One of the challenges in treating cancer is stopping it from metastasizing, and a new study reveals one of the fundamental mechanisms through which this happens. Now we know about this mechanism, perhaps we can stop it.

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AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 1, 2023

Scientists have developed a new tool for determining the age of eye cells without sampling regenerative tissue, which could make treatments for eye disease more personalized and better targeted. The team, led by researchers from Stanford University, adapted a technique used for analyzing eye fluid.

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Protein Scientist Research Development 245

AuroBlog - Aurous Healthcare Clinical Trials blog

JULY 15, 2024

Twisted and tangled proteins are found in the brains of many of those who die with Alzheimer’s disease. Some scientists suspect these neural knots can harm and even kill brain cells, but so far in clinical trials, drugs that have tried to target the tangles have shown limited success. A promising new medicine has now […]

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Clinical Trials Clinical Trials Protein Scientist 246

AuroBlog - Aurous Healthcare Clinical Trials blog

APRIL 11, 2024

Using viruses that infect bacteria to detect proteins sprouted by a notorious parasite, scientists have honed in on possible vaccine targets for schistosomiasis, a neglected tropical disease that currently affects an estimated 600 million people worldwide, causing 280,000 deaths per year.

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Pharmaceutical Technology

DECEMBER 5, 2022

Sanofi has signed an agreement with the Queensland Government in Australia to establish a $190m (A$280m) research facility in Brisbane. The hub will connect Queensland scientists with the teams at Sanofi’s mRNA Centre of Excellence in the US and France, putting them at the front of international vaccine development and biomedical research.

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Research Gene Therapy Vaccination Vaccine 246

Medical Xpress

FEBRUARY 2, 2023

Adding a molecular anchor to the key protein used to recognize cancer in cellular immunotherapies can make the treatments significantly more effective. Scientists at St.

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Scientist Protein Research 128

Scienmag

APRIL 27, 2021

Credit: UT Southwestern Medical Center DALLAS – April 27, 2021 – Researchers with the Peter O’Donnell Jr. Scientists from the departments of […].

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Protein Research Scientist Medicine 96

Medical Xpress

NOVEMBER 22, 2024

LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer.

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Development Scientist Protein Research 132

Scienmag

JUNE 22, 2022

LA JOLLA, CA—Scientists at Scripps Research have identified a protein in sensory nerves that works as a key detector of itch—specifically the “mechanical” itch stimulus of crawling insects, wool fibers, or other irritating objects that touch the skin.

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Scientist Research Protein 78

XTalks

FEBRUARY 15, 2024

In the life sciences, countless Black scientists, researchers and medical professionals have made groundbreaking discoveries that have significantly advanced our understanding of biology and medicine. Wright’s work on patient biopsy samples led to the groundbreaking use of chemotherapy as a viable cancer treatment.

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Life Science Scientist Research Protein 115

Scienmag

NOVEMBER 17, 2021

Proteins are the building blocks of all living things. A vast amount research takes place on how these proteins are made and what they do, from enzymes that carry out chemical reactions to messengers that transmit signals between cells.

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Protein Scientist Research 81

Scienmag

DECEMBER 23, 2021

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health.

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Protein Scientist Research Medicine 92

STAT News

MARCH 1, 2023

It’s an author affiliation that would make even the most seasoned scientist do a double take: New research on artificial intelligence-powered protein design, written by researchers at, of all places, Salesforce. And what are proteins, if not run-on sentences, each word another amino acid?

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Protein Scientist Research 105

Medical Xpress

APRIL 19, 2023

In research published in The FASEB Journal, scientists have discovered that a molecule called Yes-associated protein (YAP) plays a key role in the development of liver scarring, or fibrosis, by influencing the behavior of premature cells called liver progenitor cells.

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Protein Scientist Development Research 98

Scienmag

APRIL 30, 2021

Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease Credit: Salk Institute LA JOLLA–(April 30, 2021) Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells.

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Protein Scientist Research Medicine 97

Pharmaceutical Technology

DECEMBER 7, 2022

BioPIPS plans to utilise research and innovation to enhance the biologics manufacturing expertise of Singapore, which comprises recombinant therapeutic proteins and vaccines. The post GSK, Sanofi, Takeda and scientists in Singapore partner for biologics appeared first on Pharmaceutical Technology.

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XTalks

APRIL 26, 2022

California-based startup Air Protein developed an alt meat called Air Meat, which is made using microbes that turn recycled carbon dioxide (CO2) into protein. So, how does the company make alt protein out of thin air? So, how does the company make alt protein out of thin air?

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Protein Branding Production Scientist 97

Scienmag

APRIL 25, 2022

April 25, 2022—A protein that allows the fungus which causes white mold stem rot in more than 600 plant species to overcome plant defenses has been identified by a team of U.S. Department of Agriculture Agricultural Research Service and Washington State University scientists. April 25, 2022—A protein that allows […].

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Protein Scientist Research 84

Scienmag

JANUARY 25, 2022

New research, led by Washington State University scientists, into how viral proteins interact and can be disabled holds promise to help plants defend themselves against viruses—and ultimately prevent crop losses. PULLMAN, Wash. –

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Protein Scientist Research 84

Bio Pharma Dive

FEBRUARY 14, 2023

Formed by the Yale scientist and Arvinas founder, Halda Therapeutics is developing a twist on targeted protein degradation, an area of research that’s recently caught drugmakers’ attention.

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Protein Scientist Development Research 148

Scienmag

APRIL 27, 2021

Seeing the unseen: HKU scientists develop a new chemical tool that sheds light on how proteins recognise and interact with each other Credit: The University of Hong Kong A research group led by Professor Xiang David LI from the Research Division for Chemistry and the Department of Chemistry, The University of Hong Kong, has developed […].

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Protein Scientist Development Research 98

Scienmag

MAY 11, 2021

The researchers have demonstrated that silencing or inhibiting the activity of these proteins completely reverses the aortic disease in a mouse model of Marfan Syndrome Credit: CNIC Scientists at the Centro Nacional de Investigaciones Cardiovasculares Centro de Biología Molecular Severo Ochoa (CBM-CSIC-UAM) have discovered that the nitric oxide (NO) (..)

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Protein Scientist Research Cardiology 96

Scienmag

JULY 19, 2022

SAN FRANCISCO, CA—A while ago, some researchers had suggested that blocking a set of proteins, known as bromodomain and extraterminal (BET) proteins, might be a way to fight COVID-19.

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Protein Scientist Research 83

Scienmag

MARCH 29, 2021

– New research led by scientists at Washington State University has found that a protein known as GBP5 appears to play a key role in suppressing inflammation in rheumatoid arthritis, a potentially debilitating disease in which the immune system mistakenly attacks the […].

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Protein Scientist Research Allergies 88

Pharmaceutical Technology

SEPTEMBER 14, 2022

API peptides and proteins-based drugs have gained much attention in the past decade. Discover the top API protein and peptide companies in contract marketing. Technologies in the delivery of peptides and proteins. They are promising therapeutics for the treatment of a variety of metabolic and oncological disorders.

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Protein Marketing Manufacturing Reagent 100

NY Times

NOVEMBER 30, 2020

Researchers at DeepMind say they have solved “the protein folding problem,” a task that has bedeviled scientists for more than 50 years.

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Protein Scientist Drugs Research 123

Scienmag

JULY 20, 2021

New research published in the Journal of Leukocyte Biology reveals that certain protein markers may indicate which patients have stable forms of CLL and which have more aggressive types. Identifying these proteins may not only help determine patients’ prognoses but also point […].

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Protein Scientist Research Medicine 75

Medical Xpress

MAY 4, 2023

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it. While the gene was discovered more than four decades ago, researchers have so far been unsuccessful at determining exactly how it works.

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Scientist Gene Genome Genomics 104

Scienmag

MARCH 4, 2021

Findings explain how plants use RNA to defend against fungal invaders Credit: Nicole Ward Gauthier/University of Kentucky New research reveals an essential step in scientists’ quest to create targeted, more eco-friendly fungicides that protect food crops.

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Protein RNA Scientist Manufacturing 95

Medical Xpress

FEBRUARY 16, 2023

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers. In mice with colon cancer, the drug prevented or dramatically slowed formation of tumors.

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Protein Scientist Drugs Research 75

Scienmag

OCTOBER 9, 2020

Algorithms–like the ones that fill in words as people type–can learn to predict how and when proteins form different shapes.

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Protein Research Scientist 98

Scienmag

NOVEMBER 11, 2020

Yale researchers have discovered a protein that helps protect hosts from infection with the tick-borne spirochete that causes Lyme Disease, a finding that may help diagnose and treat this infection, they report Nov. 11 in the journal PLOS Pathogens.

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Protein Scientist Research Medicine 63

Medical Xpress

MARCH 1, 2023

Cholesterol tremendously increases the toxicity of a peptide implicated in Alzheimer's progression, according to research by scientists in the Department of Biochemistry and Biophysics in Texas A&M's College of Agriculture and Life Sciences.

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Protein Life Science Scientist Research 92

Scienmag

JULY 22, 2021

New UCLA research identifies TAF12 as a potential cancer drug target FINDINGS Scientists from the UCLA Jonsson Comprehensive Cancer Center have identified a key protein, transcription factor TAF12, that plays a critical role in the formation of a preinitiation complex, which consists of over one hundred proteins that are necessary for the transcription (..)

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Scientist Protein Drugs Research 75

Scienmag

AUGUST 31, 2020

A team led by a biomedical scientist at the University of California, Riverside has found a new mechanism responsible for the abnormal development of neuronal connections in the mouse brain that leads to seizures and abnormal social behaviors. The researchers […].

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Protein Scientist Development Research 97

Pharmaceutical Technology

NOVEMBER 29, 2022

Researchers at City of Hope in the US have developed a new potential therapy to treat glioblastoma multiforme (GBM), a kind of brain cancer. For this approach, the team leveraged an oncolytic herpes simplex virus for releasing chemokines, which are signalling proteins that aid in attracting immune cells to tumours.

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