AuroBlog - Aurous Healthcare Clinical Trials blog

JUNE 19, 2024

link] Checkpoint inhibitors are immunotherapy drugs that block crucial proteins from binding to cancerous tumors, meaning the immune system’s T cells can more easily […]

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Scientist Protein Drugs Research 246

AuroBlog - Aurous Healthcare Clinical Trials blog

JULY 30, 2023

Key to this newly discovered process is GRP78, and it’s what’s known as a chaperone protein. One of the challenges in treating cancer is stopping it from metastasizing, and a new study reveals one of the fundamental mechanisms through which this happens. Now we know about this mechanism, perhaps we can stop it.

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Scientist Protein Clinical Trials Clinical Trials 246

Bio Pharma Dive

SEPTEMBER 20, 2023

Targeted protein degradation has emerged as one of the more competitive areas of pharmaceutical research in recent years as scientists develop new ways to reach difficult-to-drug targets.

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Drugs Protein Scientist Development 268

AuroBlog - Aurous Healthcare Clinical Trials blog

JULY 15, 2024

Twisted and tangled proteins are found in the brains of many of those who die with Alzheimer’s disease. Some scientists suspect these neural knots can harm and even kill brain cells, but so far in clinical trials, drugs that have tried to target the tangles have shown limited success. A promising new medicine has now […]

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Clinical Trials Clinical Trials Protein Scientist 246

AuroBlog - Aurous Healthcare Clinical Trials blog

APRIL 11, 2024

Using viruses that infect bacteria to detect proteins sprouted by a notorious parasite, scientists have honed in on possible vaccine targets for schistosomiasis, a neglected tropical disease that currently affects an estimated 600 million people worldwide, causing 280,000 deaths per year.

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Vaccination Vaccine Bacteria Protein 240

AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 1, 2023

Scientists have developed a new tool for determining the age of eye cells without sampling regenerative tissue, which could make treatments for eye disease more personalized and better targeted. Almost 6,000 proteins detected in the fluid could be traced […]

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Protein Scientist Research Development 245

Scienmag

DECEMBER 15, 2021

Scientists tested V-SYNTHES on the protein receptors affected by the active ingredient in marijuana, […]. Key takeaways: Credit: USC Dornsife/Yekaterina Kadyshevskaya Key takeaways: New technology called “V-SYNTHES” uncovers more effective drug candidates in a fraction of the time other algorithms need.

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Scientist Drugs Protein 130

Medical Xpress

FEBRUARY 2, 2023

Adding a molecular anchor to the key protein used to recognize cancer in cellular immunotherapies can make the treatments significantly more effective. Scientists at St.

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Scientist Protein Research 117

Scienmag

NOVEMBER 22, 2021

Scientist are now combining recent advances in evolutionary analysis and deep learning to build three-dimensional models of how most proteins in eukaryotes interact.

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Protein Scientist Genetics Medicine 90

Scienmag

JULY 15, 2021

New artificial intelligence software can compute protein structures in 10 minutes Credit: Ian Haydon, UW Medicine Institute for Protein Design Scientists have waited months for access to highly accurate protein structure prediction since DeepMind presented remarkable progress in this area at the 2020 Critical Assessment of Structure Prediction, or (..)

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Protein Scientist Medicine Engineer 98

STAT News

DECEMBER 2, 2022

A Somerville startup and an academic lab in Seattle say they have developed a way to use artificial intelligence to design proteins that don’t exist in nature. Proteins help people move, digest food, and fight infections — to name a few of their numerous functions. And for some scientists, nature is too limiting.

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Protein Scientist Development Drugs 111

Scienmag

NOVEMBER 17, 2021

Proteins are the building blocks of all living things. A vast amount research takes place on how these proteins are made and what they do, from enzymes that carry out chemical reactions to messengers that transmit signals between cells.

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Protein Scientist Research 81

Scienmag

APRIL 8, 2021

Credit: © Terence Strick The Mfd protein repairs bacterial DNA, but can also, to scientists’ surprise, promote mutation. Understanding this second “role” of the Mfd protein opens up opportunities for combating antibiotic resistance, and also the resistance of tumours to anti-cancer drugs and therapies.

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Protein DNA Scientist Drugs 98

XTalks

APRIL 26, 2022

California-based startup Air Protein developed an alt meat called Air Meat, which is made using microbes that turn recycled carbon dioxide (CO2) into protein. So, how does the company make alt protein out of thin air? After that, in a process like beer fermentation, the protein is turned into a flour-like substance.

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Protein Branding Production Scientist 97

Pharma Times

AUGUST 13, 2024

The V-ATPase protein, V1H, was found to be involved in the process of raising the alarm

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Scientist Protein 134

Medical Xpress

NOVEMBER 22, 2024

LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer.

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Development Scientist Protein Research 124

Scienmag

DECEMBER 23, 2021

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health.

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Protein Scientist Research Medicine 92

Scienmag

DECEMBER 16, 2021

For nearly 50 years, scientists have struggled to solve one of nature’s most perplexing challenges – predicting the complex 3D shape a string of amino acids will fold into as it becomes a working protein.

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Protein Scientist 86

Scienmag

APRIL 19, 2022

Scientists have known for years that amyloid fibrils — fibrous, ropelike structures formed by closely linked protein molecules — are present in the brains of patients with Alzheimer’s and Parkinson’s diseases and likely play a role in the progression of these disorders. Scientists have known for years that amyloid […].

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Protein Scientist 89

XTalks

FEBRUARY 15, 2024

In the life sciences, countless Black scientists, researchers and medical professionals have made groundbreaking discoveries that have significantly advanced our understanding of biology and medicine. They serve as inspiration for future generations of scientists from all backgrounds.

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Life Science Scientist Research Protein 115

Scienmag

APRIL 30, 2021

Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease Credit: Salk Institute LA JOLLA–(April 30, 2021) Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells.

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Protein Scientist Research Medicine 97

STAT News

MARCH 1, 2023

It’s an author affiliation that would make even the most seasoned scientist do a double take: New research on artificial intelligence-powered protein design, written by researchers at, of all places, Salesforce. And what are proteins, if not run-on sentences, each word another amino acid?

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Protein Scientist Research 105

Scienmag

FEBRUARY 10, 2022

Soybeans outmatch all other legumes as the protein powerhouses of the plant kingdom, providing a key protein source for humans and livestock around the world. And now, after 30 years, University of Illinois scientists have identified the gene with the largest impact on seed protein in soybean. URBANA, Ill.

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Protein Gene Scientist 86

Scienmag

APRIL 27, 2021

Brain Institute at UT Southwestern have identified a new protein implicated in cell death that provides a potential therapeutic target that could prevent or delay the progress of neurodegenerative diseases following a stroke. Scientists from the departments of […].

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Protein Research Scientist Medicine 96

Scienmag

APRIL 25, 2022

April 25, 2022—A protein that allows the fungus which causes white mold stem rot in more than 600 plant species to overcome plant defenses has been identified by a team of U.S. Department of Agriculture Agricultural Research Service and Washington State University scientists. April 25, 2022—A protein that allows […].

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Protein Scientist Research 84

Scienmag

JANUARY 25, 2022

New research, led by Washington State University scientists, into how viral proteins interact and can be disabled holds promise to help plants defend themselves against viruses—and ultimately prevent crop losses. PULLMAN, Wash. –

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Protein Scientist Research 84

STAT News

OCTOBER 13, 2022

Every two years since 1994, scientists have come together for an experiment — better described as a competition — where teams of computational biologists try to predict what proteins will look like in 3D given their amino acid sequence. In 2020, its successor, AlphaFold2, achieved near-perfect scores.

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Protein Scientist Drugs Development 111

Scienmag

DECEMBER 10, 2020

A team of Gladstone and UCSF scientists used a large-scale genetic approach to map the structure of protein complexes in live cells Credit: QBI, UCSF SAN FRANCISCO, CA–December 10, 2020–One of biologists’ most vexing tasks is figuring out how proteins, the molecules that carry the brunt of a cell’s work, do their job.

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Protein Genetics Scientist 86

Scienmag

SEPTEMBER 22, 2021

CHAPEL HILL, NC – Mucus is an essential protective layer of gel-like liquid composed largely of proteins called mucins throughout our airways. One of them, called MUC5B, is crucial for the innate defense against the various things we inhale.

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Protein Scientist Medicine 77

Pharmaceutical Technology

SEPTEMBER 14, 2022

API peptides and proteins-based drugs have gained much attention in the past decade. Discover the top API protein and peptide companies in contract marketing. Technologies in the delivery of peptides and proteins. They are promising therapeutics for the treatment of a variety of metabolic and oncological disorders.

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Protein Marketing Manufacturing Reagent 100

Pharmaceutical Technology

DECEMBER 7, 2022

BioPIPS plans to utilise research and innovation to enhance the biologics manufacturing expertise of Singapore, which comprises recombinant therapeutic proteins and vaccines. The post GSK, Sanofi, Takeda and scientists in Singapore partner for biologics appeared first on Pharmaceutical Technology.

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Scientist Manufacturing Vaccination Vaccine 130

Scienmag

JANUARY 25, 2022

An international team of scientists has determined the precise structural changes in the spike protein of the omicron variant. Credit: David Veesler Lab An international team of scientists has determined the precise structural changes in the […].

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Protein Scientist Antibody 79

Scienmag

APRIL 27, 2022

Credit: CNIC Scientists […].

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Scientist Protein 86

Scienmag

JULY 19, 2022

SAN FRANCISCO, CA—A while ago, some researchers had suggested that blocking a set of proteins, known as bromodomain and extraterminal (BET) proteins, might be a way to fight COVID-19.

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Protein Scientist Research 83

Scienmag

MAY 11, 2021

The researchers have demonstrated that silencing or inhibiting the activity of these proteins completely reverses the aortic disease in a mouse model of Marfan Syndrome Credit: CNIC Scientists at the Centro Nacional de Investigaciones Cardiovasculares Centro de Biología Molecular Severo Ochoa (CBM-CSIC-UAM) have discovered that the nitric oxide (NO) (..)

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Protein Scientist Research Cardiology 96

Scienmag

JUNE 22, 2022

LA JOLLA, CA—Scientists at Scripps Research have identified a protein in sensory nerves that works as a key detector of itch—specifically the “mechanical” itch stimulus of crawling insects, wool fibers, or other irritating objects that touch the skin.

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Scientist Research Protein 78

Scienmag

DECEMBER 22, 2021

Although these lineages split more than 300 million years ago, their venoms have evolved from the same ancestral salivary protein, reported scientists today in BMC Biology. Snakes, some lizards and even a few mammals can have a venomous bite.

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Protein Scientist 89