Bio Pharma Dive

JANUARY 6, 2022

The Swiss pharma is well familiar with Alnylam's RNA-based technology, which underpins Novartis' newly approved cholesterol drug Leqvio.

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Bio Pharma Dive

FEBRUARY 28, 2023

An alliance with the startup brings Vertex an RNA-based medicine for the disease, adding to a portfolio that already includes a gene editing treatment.

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Bio Pharma Dive

SEPTEMBER 9, 2021

billion, expands Lilly's work in genetic medicine research. An agreement with the Dutch biotech, which could be worth as much as $1.3

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Pharmaceutical Technology

JUNE 16, 2023

Flamingo Therapeutics has received a research grant of €1.7m from Flanders Innovation & Entrepreneurship (VLAIO) to further advance its oncology portfolio targeting RNA. It will also support the firm’s preclinical effort on the long non-coding RNA (LncRNA) programme, FTX-001, that targets MALAT-1.

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Bio Pharma Dive

NOVEMBER 29, 2022

In this continuing series, BioPharma Dive examines new areas of biotech investment and startup activity, such as next-generation RNA medicines, TYK2 inhibitors and in vivo CAR-T.

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Bio Pharma Dive

MAY 19, 2023

The biotech, best known for its vaccine research, said its clinical trial is the first to report results of a messenger RNA therapeutic designed for intracellular protein replacement.

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Pharmaceutical Technology

MARCH 1, 2023

Further, the acceptance of new mRNA vaccines has rejuvenated activity within previously established categories of RNA therapeutics including lifesaving antisense technologies. These include antisense oligonucleotides (ASO), RNA interference (RNAi), and RNA aptamers.

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Pharmaceutical Technology

JUNE 19, 2024

Ascidian has entered a research partnership and licensing agreement with Roche to develop RNA therapies for neurological diseases.

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Pharmaceutical Technology

SEPTEMBER 5, 2024

A panel of researchers gave presentations on the clinical evidence for the role of RNA in therapy for cardiovascular conditions.

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AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 1, 2023

The Drug Controller General of India (DCGI) has added in-vitro diagnostic (IVD) medical devices including those for diagnosis of Covid-19, ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) extraction kits, among others into the Class C risk category under the Medical Devices Rules (MDR), 2017.

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Pharmaceutical Technology

AUGUST 17, 2022

Merck (MSD outside North America) has entered a partnership agreement with Orna Therapeutics for discovering, developing and marketing various programmes based on next-generation RNA technology. By self-circularisation, Orna’s oRNA technology makes circular ribonucleic acids (oRNAs) from linear RNAs.

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Pharmaceutical Technology

OCTOBER 11, 2022

Biotechnology company Ochre Bio has raised $30m in a Series A financing round to develop RNA therapies for chronic liver diseases. It also intends to turn the insights from its research into RNA-based drug candidates, and they will be tested in human livers at the company’s recently opened ‘Liver ICUs’ in the US.

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Bio Pharma Dive

JUNE 3, 2024

The alliance hands Lilly an RNA-based therapy in preclinical testing for ALS and frontotemporal dementia, and includes a research collaboration to develop other, similar medicines.

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XTalks

SEPTEMBER 13, 2021

With RNA therapies being the next hot thing in genetic medicine, Eli Lilly is joining the RNA editing race by partnering with Netherlands-based ProQR Therapeutics NV (Nasdaq: PRQR), a biotech company developing RNA-based therapies for rare genetic diseases with a focus on blinding disorders of the retina.

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Pharma Times

JANUARY 6, 2021

Test can give accurate results in under five minutes, according to researchers

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XTalks

NOVEMBER 9, 2021

Perhaps popularized by the COVID-19 vaccines, RNA-based technologies now have the potential to become the next best pesticide to combat crop pests, like insects and fungal pathogens. Over the last year, researchers have been studying the effectiveness of RNA-based pesticides, and there are already a handful of sprays in the works.

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pharmaphorum

MAY 30, 2024

Discover how genomics is transforming cancer research through the study of DNA, RNA, and ctDNA. Learn about the latest breakthroughs in the field in this insightful short read.

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Pharmaceutical Technology

FEBRUARY 9, 2023

ReviR Therapeutics has signed a research collaboration and option-to-license agreement with Asieris Pharmaceuticals to discover new oncology therapeutics. The company’s VoyageR AI platform integrates computational methods to drug traditionally undruggable RNA targets.

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Scienmag

APRIL 14, 2021

Credit: Surajit Chatterjee To better understand how RNA in bacteria gives rise to protein–and along the way, target these processes in the design of new antibiotics–researchers are turning their attention to the unique way this process happens in bacteria.

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Bio Pharma Dive

JULY 27, 2021

The companies said that patients treated with their experimental drug BIIB080 had reductions in a protein called tau, which research indicates is tied to Alzheimer's but isn't yet proven to impact the course of the disease.

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Medical Xpress

DECEMBER 20, 2022

The research also uncovered a new way to boost the effectiveness of RNA therapies by controlling this "fighting back" activity.

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Bio Pharma Dive

OCTOBER 6, 2022

A new agreement with the Australian government will bring messenger RNA research and manufacturing capabilities to the country, adding to the COVID-19 vaccine developer’s global expansion efforts.

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Pharma Mirror

SEPTEMBER 2, 2021

In-vitro studies conducted at the British virology research laboratory Virology Research Services in London then demonstrated a potent antiviral activity against SARS-CoV-2 and other RNA viruses. The trial was conducted at.

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Scienmag

MARCH 9, 2022

A team led by scientists at the University of Birmingham has come a step closer to uncovering the purpose of a distinctive set of modifications found at the beginning of messenger RNA which have long remained a fundamental mystery in molecular biology. Messenger RNAs (mRNAs) are vital for protein production.

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Scienmag

JANUARY 22, 2021

Cryo-electron microscopy study allows researchers to visualize structural changes in an E.

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pharmaphorum

JANUARY 19, 2022

Research into single-cell sequencing has been boosted with Single Cell Discoveries and BioTuring joining forces to refine the process. A rapidly growing field of research, single-cell RNA sequencing is vital for those working in areas such as oncology, immunology, and neuroscience.

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Scienmag

APRIL 19, 2022

A research team led by scientists from the Hong Kong University of Science and Technology (HKUST) has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate (..)

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AuroBlog - Aurous Healthcare Clinical Trials blog

FEBRUARY 11, 2025

Researchers from Arizona State University suggest that stress granules protein and RNA clumps that form around cells in stressful […]

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BioSpace

APRIL 21, 2024

Ipsen is looking to deepen its expertise in movement disorders in a research collaboration with Skyhawk Therapeutics to develop small molecule drugs for RNA targets in neurological diseases.

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Scienmag

MAY 3, 2022

LA JOLLA, CA—Scientists at Scripps Research have unveiled a new software tool for studying RNA (ribonucleic acid) molecules, which have a host of critical roles in organisms.

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Medical Xpress

MAY 18, 2023

Our bodies burn carbohydrates, proteins, and fat for fuel, and now, researchers at the Broad Institute of MIT and Harvard and the University of Lausanne have discovered another important energy source for cells: uridine, the chemical building block unique to RNA.

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Bio Pharma Dive

DECEMBER 22, 2020

Following a string of deals in edgy, unproven fields of scientific research, Vertex's latest diversification push involves chemical-based drugs that target RNA — an approach that's already attracted several large pharmas.

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Bio Pharma Dive

SEPTEMBER 14, 2022

Capstan Therapeutics was formed by pioneering CAR-T and messenger RNA researchers, and has secured funding from five large drugmakers.

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Pharmaceutical Technology

AUGUST 1, 2022

The company will jointly design and analyse messenger ribonucleic acid (mRNA) Covid-19 vaccines in partnership with the NIH unit National Institute of Allergy and Infectious Diseases’ Vaccine Research Center (VRC). They intend to develop vaccines that provide lasting immune responses compared to existing vaccines.

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AuroBlog - Aurous Healthcare Clinical Trials blog

OCTOBER 16, 2022

The husband-and-wife team who co-founded BioNTech, the biotechnology company that partnered with Pfizer to develop an effective messenger-RNA (mRNA) shot against COVID-19, has predicted that a cancer vaccine could be widely available within the next decade.

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Scienmag

APRIL 8, 2022

Tokyo University of Agriculture and Technology researchers reported on a new discovery regarding the mechanisms for bone loss in gum disease (periodontitis). They found that double stranded RNA molecules can activate the immune system response that leads to deterioration of bone.

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XTalks

MARCH 21, 2022

Credited as a pioneering RNA interference (RNAi) therapeutics company, Alnylam Pharmaceuticals is taking Pfizer and Moderna to court, claiming that the companies’ use of the lipid nanoparticle (LNP)-based RNA delivery technology in their mRNA COVID-19 vaccines infringes on a patented technology.

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