Pharmaceutical Technology

APRIL 20, 2023

Targovax has unveiled plans to rebrand as Circio , reflecting its strategic shift to focus on expediting the development of its innovative circular RNA (circRNA) platform. Initially reported in 2011, CircRNA is a naturally occurring class of RNA.

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Gene Therapy RNA Gene Development 240

Scienmag

MARCH 9, 2022

A team led by scientists at the University of Birmingham has come a step closer to uncovering the purpose of a distinctive set of modifications found at the beginning of messenger RNA which have long remained a fundamental mystery in molecular biology. Messenger RNAs (mRNAs) are vital for protein production.

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RNA Research Protein Scientist 80

Scienmag

JULY 6, 2022

Army scientists and industry partners were among the first to demonstrate that messenger RNA (mRNA)—the technology recently used in COVID-19 vaccines and others—could also be used to develop treatments for infectious diseases. Credit: Study: USAMRIID / […].

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RNA Development Scientist Vaccine 81

Scienmag

SEPTEMBER 29, 2021

JUPITER, FL – The American Chemical Society announced that its prestigious 2022 Nobel Laureate Signature Award for Graduate Education in Chemistry honors a student from the Skaggs Graduate School of Chemical and Biological Sciences at Scripps Research and her faculty advisor, for their pioneering work developing RNA-targeting medications for genetic (..)

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RNA Genetic Disease Scientist Genetics 77

Scienmag

APRIL 19, 2022

A research team led by scientists from the Hong Kong University of Science and Technology (HKUST) has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate (..)

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RNA Research Scientist 82

Medical Xpress

APRIL 28, 2023

A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics. The study, led by Gustavo Garcia Jr. The study, led by Gustavo Garcia Jr.

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Scientist RNA 104

Scienmag

APRIL 27, 2021

Credit: Nigel Michki Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells that eventually become neurons.

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RNA Scientist Gene Development 98

Scienmag

MAY 3, 2022

LA JOLLA, CA—Scientists at Scripps Research have unveiled a new software tool for studying RNA (ribonucleic acid) molecules, which have a host of critical roles in organisms.

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RNA Development Research Drugs 77

Medical Xpress

APRIL 25, 2023

A team of international scientists led by the Heidelberg University, Medical Faculty Mannheim, and the Newcastle University (Great Britain) has succeeded in decoding a new mechanism of immune cell trafficking by examining vascular diseases.

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RNA Scientist 75

pharmaphorum

JANUARY 19, 2022

The collaboration aims to “close the gap between single-cell RNA sequencing wet-lab services and single-cell data analysis solutions,” which will allow scientists to study the finest details that can be hard to access. The post BioTuring enters collaboration to enable detailed single-cell RNA research appeared first on.

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RNA Research Life Science Bioinformatics 72

Medical Xpress

MARCH 1, 2023

Scientists have found a novel way to block the transportation of mutant RNA and subsequent production of toxic repeat proteins that lead to the death of nerve cells in the most common subtypes of motor neuron disease (MND) and frontotemporal dementia (FTD).

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Scientist RNA Protein Production 80

pharmaphorum

OCTOBER 18, 2021

SMi Group’s 13th Annual Conference: RNA Therapeutics 2022. Bolstering the latest advances and opportunities in RNA-based medicine. Delve into the latest innovations in novel RNA delivery and target specificity. Engage in the growing advances and development of RNA tools for vaccines and anti-infectives. Senior Scientists.

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RNA Drug Delivery Scientist Clinical Development 52

Scienmag

JUNE 9, 2022

NEW YORK, JUNE 9, 2022 – In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house. Credit: Memorial Sloan Kettering Cancer Center NEW YORK, JUNE […].

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RNA Scientist Protein 84

Pharma Mirror

APRIL 21, 2024

Scientists have been striving to optimize mRNA stability, immunogenicity, translation efficiency, and delivery systems to achieve efficient and safe mRNA delivery. Messenger RNA (mRNA) is a single-stranded ribonucleic acid transcribed from the DNA chain, carrying the encoding information for protein synthesis.

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In-Vitro Drugs Genetic Disease RNA 130

pharmaphorum

NOVEMBER 1, 2022

14th Annual RNA Therapeutics. Investigating the next generation of genetic medicine through RNA based therapies. RNA therapeutics is a rapidly expanding industry with increasingly growing potential for immunotherapy, personalised medicines, and treatment of genetic, infectious, and chronic diseases. Date: 8 – 9 February 2023.

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RNA Genetics Gene Editing In-Vitro 52

Scienmag

APRIL 27, 2022

CHAPEL HILL, NC – Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA – a crucial regulatory step before proteins are created. Then, organs develop and hopefully function properly.

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Scientist Gene RNA Protein 83

Scienmag

MAY 7, 2021

The disorder, scientists found, is caused […].

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Medical Xpress

DECEMBER 30, 2022

Messenger RNA vaccine technology, once an arcane area of research, became household terminology because of the COVID-19 pandemic, and now scientists are working on an mRNA flu vaccine strategy that, at least in this study, involves a first dose administered as a shot but a booster administered as an mRNA nasal spray.

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Vaccination Vaccine RNA Scientist 111

Scienmag

MAY 3, 2021

Researchers who elucidated key functions of RNA, the workhorse molecule of cells, will be honored in October The 2021 Warren Alpert Foundation Prize has been awarded to scientists Lynne Maquat and Joan Steitz for seminal discoveries in the biology and function of RNA, the workhorse molecule of cells.

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RNA Scientist Research Allergies 41

Scienmag

NOVEMBER 6, 2020

JUPITER, FL–A new strategy for treating a variety of diseases known as RNA-repeat expansion disorders, which affect millions of people, has shown promise in proof-of-principle tests conducted by scientists at […].

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RNA Scientist Research Genetics 60

Medical Xpress

FEBRUARY 2, 2023

A new microfluidic device developed by scientists in Switzerland can detect the SARS-CoV-2 virus with high accuracy and speed, using a unique DNA/RNA duplex technology. The device could prove to be a game-changer in the fight against the ongoing COVID-19 pandemic.

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Scienmag

MARCH 4, 2021

Findings explain how plants use RNA to defend against fungal invaders Credit: Nicole Ward Gauthier/University of Kentucky New research reveals an essential step in scientists’ quest to create targeted, more eco-friendly fungicides that protect food crops.

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Protein RNA Scientist Manufacturing 95

Scienmag

OCTOBER 7, 2020

New technique breaks through a technology roadblock that limited RNA imaging for 50 years Credit: Kwaku Dayie/University of Maryland University of Maryland scientists have developed a method to determine the structures of large RNA molecules at high resolution.

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RNA Development Scientist Research 52

Scienmag

MAY 5, 2021

Transcription is a vital process in bacterial cell, where genetic information in DNA is transcribed to RNA for the translation of proteins that perform cellular function. Credit: The Hong Kong University of Science and Technology The emergence and spread of new forms of resistance remains a concern that urgently demand new antibiotics.

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Scienmag

JUNE 2, 2021

Credit: Ron Bend/CSU A team of Colorado State University scientists, led by veterinary postdoctoral fellow Dr. Anna Fagre, has detected Zika virus RNA in free-ranging African bats. RNA, or ribonucleic acid, is a molecule that plays a central role in the function of genes.

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RNA Research Gene Scientist 52

BioTech 365

JUNE 1, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists develop new method for ultra-high-throughput RNA sequencing in single cells.RNA sequencing is a powerful technology for studying cells and diseases.

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RNA Scientist Development Research 40

BioTech 365

NOVEMBER 23, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scientists reveal role of RNA helicase in zygote activation and stem cell homeostasis in plants.After double fertilization, zygotic activation occurs that initiates a new life cycle, followed … Continue reading →

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RNA Scientist Research 40

Scienmag

MARCH 9, 2021

Scientists from the CNRS, INSERM, the AP-HP and the […]. It affects the peripheral nerves and causes progressive paralysis of the legs and hands. No treatment is currently available to fight this disease, which is due to the overexpression of a specific protein.

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RNA Protein Scientist Medicine 73

The Pharma Data

JUNE 14, 2023

Scientists discover small RNA that regulates bacterial infection People with weakened immune systems are at constant risk of infection. Interestingly, the researchers found that rather than encoding a protein, the gene encodes a small RNA that plays a vital role in bacterial respiration. aeruginosa infections.

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RNA Regulation Scientist Bacteria 40

Scienmag

APRIL 26, 2022

Using new analyses, scientists have just found the last two of the five informational units of DNA and RNA that had yet to be discovered in samples from meteorites. While it is unlikely that DNA could be formed in a meteorite, this discovery demonstrates that these genetic parts are available for delivery and could have […].

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DNA RNA Genetics Scientist 86

STAT News

AUGUST 17, 2022

  The hunt for cancer cures has, to a large degree, been a hunt for biomarkers — DNA, peptides, RNA, proteins or more — that might set tumor cells apart from healthy tissue. On Target is a recurring feature from STAT that dives deep into the most promising drug targets in oncology. 

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RNA DNA Protein Scientist 98

Scienmag

JANUARY 13, 2022

14, 2022) – A molecule of RNA called CARMN has been found in abundance in the healthy smooth muscle cells that help give our blood vessels strength and flexibility, and distinctly decreased in vascular diseases like atherosclerosis, a major cause of heart attack and stroke, scientists report. AUGUSTA, Ga.

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RNA Scientist Medicine 83

XTalks

OCTOBER 21, 2020

The answer may lie in the genetic code of the virus, which scientists at Duke University have found contains several silent mutations that affect protein folding. Moreover, Berrio says the changes likely affected the folding and function of viral RNA. These mutations may thus be “silent” as they do not alter protein structure.

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RNA Protein Genomics Genome 98

XTalks

OCTOBER 8, 2024

The 2024 Nobel Prize in Physiology or Medicine has been awarded to American scientists Victor Ambros and Gary Ruvkun for their groundbreaking discovery of microRNA (or miRNA) and its role in post-transcriptional gene regulation. Their ability to modulate gene expression at the RNA level provides a novel therapeutic approach for conditions.

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Regulation Genetics Scientist RNA 52

STAT News

OCTOBER 21, 2022

Thirty years ago, Katalin Karikó had what was then an outlandish idea: use messenger RNA as a medicine. One rejection she might now be able to laugh about was a research opportunity with funding for six scientists. But getting funding to demonstrate that might be possible was impossible, despite three decades of trying.

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Research RNA Scientist Vaccine 98

Medical Xpress

FEBRUARY 9, 2023

A team of medical scientists working at the University of Pennsylvania's Perelman School of Medicine has used single-nucleus RNA sequencing to isolate those mouse liver cells cells that push the progression of nonalcoholic fatty liver disease (NAFLD) into non-alcoholic steatohepatitis (NASH), where fibroids develop, which typically means permanent (..)

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RNA Scientist Medicine Development 80

STAT News

NOVEMBER 4, 2022

Previously, she worked at Moderna, where she was director of RNA science. Before that, she spent 20 years as a research scientist at the Massachusetts Institute of Technology. This time around, we note that Alltrna hired Caroline Kӧhrer as vice president, discovery platform. Continue to STAT+ to read the full story…

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RNA Scientist Research 97