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STAT+: A new suite of RNA-sensing tools could help scientists target cancerous cells, and much more

STAT News

That stands for “adenosine deaminases acting on RNA.” But this RNA-editing class of proteins, made by all multicellular organisms, is starting to have its moment in the bioengineering sun. Sure, you’ve heard of CRISPR. But it’s 2022. The acronym you need to know now is ADARs. ” Catchy it may not be.

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Scientists develop an RNA-based breath test to detect COVID-19

Scienmag

Philadelphia, December 13, 2021 – In a new study in The Journal of Molecular Diagnostics, published by Elsevier, investigators report on the design and testing of a breathalyzer, known as the Bubbler, that relies on viral RNA detection to diagnose SARS-CoV-2.

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Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Medical Xpress

Scientists at University of Florida (UF) Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The compound restored the health of neurons in the lab and rescued mice with the disease.

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Blocking a tiny RNA may forestall age-related bone and muscle loss, inflammation

Medical Xpress

Inhibiting a tiny RNA whose levels significantly increase with age, along with problems like weaker bones and sagging muscles, may be a way to keep our bodies more youthful and healthy, scientists say.

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RNA editing protein ADAR1 protects telomeres and supports proliferation in cancer cells

Scienmag

Credit: The Wistar Institute PHILADELPHIA — (March 12, 2021) — Scientists at The Wistar Institute identified a new function of ADAR1, a protein responsible for RNA editing, discovering that the ADAR1p110 isoform regulates genome […].

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???????Research sheds light on mysterious messenger RNA modifications

Scienmag

A team led by scientists at the University of Birmingham has come a step closer to uncovering the purpose of a distinctive set of modifications found at the beginning of messenger RNA which have long remained a fundamental mystery in molecular biology. Messenger RNAs (mRNAs) are vital for protein production.

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Scientists behind RNA-repairing strategy recognized with American Chemical Society’s Nobel Signature award

Scienmag

JUPITER, FL – The American Chemical Society announced that its prestigious 2022 Nobel Laureate Signature Award for Graduate Education in Chemistry honors a student from the Skaggs Graduate School of Chemical and Biological Sciences at Scripps Research and her faculty advisor, for their pioneering work developing RNA-targeting medications for genetic (..)

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