GSK hires away top Pfizer vaccine scientist
Bio Pharma Dive
NOVEMBER 30, 2021
Philip Dormitzer, who helped Pfizer develop shots for COVID-19, RSV and influenza, will become the British pharma's head of vaccine R&D next month.
Extreme Case of Man Who Had 217 COVID Vaccines Surprises Scientists
AuroBlog - Aurous Healthcare Clinical Trials blog
MARCH 12, 2024
That’s how many vaccines a man in Germany claims to have received for COVID-19 in just 29 months – and his body isn’t reacting the way some scientists thought it would. Two hundred and seventeen. The 62-year-old male from the city of Magdeburg made headlines a few years ago for his private and risky decision […]
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FDA weighs shift in COVID vaccination strategy
Bio Pharma Dive
JANUARY 23, 2023
Agency scientists are proposing to update COVID shots once a year to match circulating coronavirus strains, as well as simplifying current vaccination regimens.
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FDA review supports safety, efficacy of J&J coronavirus vaccine
Bio Pharma Dive
FEBRUARY 24, 2021
Agency scientists noted the shot's strong protection against severe COVID-19, even for the virus variant first detected in South Africa and known to weaken vaccine potency.
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FDA scientists back safety, efficacy of Moderna's coronavirus vaccine
Bio Pharma Dive
DECEMBER 15, 2020
A review by agency staff affirmed the strongly positive results Moderna reported from a large Phase 3 study, clearing the way for a possible emergency authorization in the coming days.
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Russia, with scant study data, approves coronavirus vaccine
Bio Pharma Dive
AUGUST 11, 2020
The shot, developed by the state-backed Gamaleya Research Institute, hasn't yet been tested in the large, placebo-controlled tests scientists emphasize are needed to prove a vaccine is protective.
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FDA names new head to vaccine review office
Bio Pharma Dive
SEPTEMBER 9, 2022
David Kaslow, the lead scientist at a global public health nonprofit, will succeed Marion Gruber, who retired last fall amid her dissent on the timing of COVID-19 vaccine boosters.
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Breakthrough Vaccine Shows High Protection Against Drug-Resistant Superbug in Mice
AuroBlog - Aurous Healthcare Clinical Trials blog
MAY 1, 2024
Scientists have developed a vaccine against a notorious drug-resistant superbug, targeting molecules on its surface that are also found on other bacteria and fungi.
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Radical Vaccine Strategy Could Help Quash Parasite Afflicting Millions
AuroBlog - Aurous Healthcare Clinical Trials blog
APRIL 11, 2024
Using viruses that infect bacteria to detect proteins sprouted by a notorious parasite, scientists have honed in on possible vaccine targets for schistosomiasis, a neglected tropical disease that currently affects an estimated 600 million people worldwide, causing 280,000 deaths per year.
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Malaria Could Be Eliminated by 2040: New Vaccine Offers Hope
AuroBlog - Aurous Healthcare Clinical Trials blog
OCTOBER 8, 2023
The World Health Organization has approved a new vaccine that scientists argue will be a game-changer in the fight against malaria, which kills half a million people in Africa every year.
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FDA scientists appear supportive of Pfizer, BioNTech's coronavirus vaccine
Bio Pharma Dive
DECEMBER 8, 2020
Agency staff didn't raise any red flags in their review of the companies' study results, documents released ahead of a key advisory committee meeting Thursday show.
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Valneva’s Lyme disease vaccine faces final clinical test in a sparse landscape
Pharmaceutical Technology
AUGUST 17, 2022
On August 8, Pfizer and Valneva announced the initiation of a Phase III study with their Lyme disease vaccine , bringing the prospect of an injection to prevent the condition disease one step closer to reality. This means that the vaccine works against multiple serotypes of the disease, she explains. A one-size-fits-all approach.
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Pfizer research chief Dolsten to step down, with company at a crossroads
Bio Pharma Dive
JULY 9, 2024
The company has begun searching for a successor to Dolsten, who oversaw more than 35 drug and vaccine approvals but also some notable setbacks during his time as Pfizer’s top scientist.
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Moderna, Pfizer ready multi-pronged plans for coronavirus variants
Bio Pharma Dive
FEBRUARY 24, 2021
Moderna has delivered a modified version of its vaccine to NIH scientists, while Pfizer has begun testing of an additional booster shot in a clinical trial, both precautionary steps against emerging strains.
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Moderna, escalating dispute with NIH, claims government had no role in key vaccine patent
Bio Pharma Dive
NOVEMBER 11, 2021
The biotech claimed its NIH partners were involved only after a key discovery was made "by Moderna scientists using Moderna technology." " The dispute could end up in court.
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Moderna readies multi-pronged plan for coronavirus variants, ups vaccine production
Bio Pharma Dive
FEBRUARY 24, 2021
The biotech has delivered a newly developed booster shot to NIH scientists, and will test several other approaches to address emerging virus strains.
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Vaccine Makers Keep Safety Details Quiet, Alarming Scientists
NY Times
SEPTEMBER 13, 2020
Researchers say drug companies need to be more open about how vaccine trials are run to reassure Americans who are skittish about getting a coronavirus vaccine.
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Pfizer/BioNTech vaccine may work against new virus mutation, scientists say
pharmaphorum
JANUARY 8, 2021
The Pfizer/BioNTech vaccine appears to work against an important mutation in the new coronavirus variants causing havoc in the UK and South Africa, according to research from the drugs giant. The study team tested blood taken from people who had received the mRNA vaccine developed by BioNTech and Pfizer.
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DBT to support multi institutional CoEs for nano-vaccines and nano-adjuvants development
AuroBlog - Aurous Healthcare Clinical Trials blog
DECEMBER 14, 2022
The Department of Biotechnology (DBT) is extending support to the institutions and scientists to set up Centres of Excellence in the country for nano-vaccines and nano-adjuvants, to treat cancer and other diseases.The Department has invited Letters of Intent (LoIs) for ‘Setting up of CoE in Nano-Vaccines & Nano-Adjuvants’ for a period of five years (..)
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FDA scientists propose an annual Covid shot matched to current strains
STAT News
JANUARY 23, 2023
Scientists at the Food and Drug Administration propose making Covid vaccination a regular, once-a-year shot that is updated to match current strains of the SARS-CoV-2 virus, according to documents posted by the FDA on Monday. For people who are older or immunocompromised, the FDA would recommend two annual doses of the revised shot.
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Scientists Explore SARS-CoV-2 Mega Vaccine
BioSpace
NOVEMBER 10, 2021
?Scientists are conducting research into the possibility of creating a vaccine that activates T cells that targets not just SARS-CoV-2 but also its variations, even the ones that cause common colds.
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Scientists behind mRNA Covid vaccines win Nobel Prize
BioPharma Reporter
OCTOBER 3, 2023
The Nobel Prize in medicine has been awarded to two scientists who developed the technology which led to the mRNA vaccines against COVID-19.
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Going all the way: Scientists prove that inhaled vaccines offer better protection and immunity than nasal sprays
Scienmag
JUNE 9, 2022
HAMILTON, June 10, 2022–McMaster University scientists who compared respiratory vaccine-delivery systems have confirmed that inhaled aerosol vaccines provide far better protection and stronger immunity than nasal sprays.
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Scientists and medics turn to TikTok to reassure public on vaccine safety
pharmaphorum
DECEMBER 17, 2020
Tik Tok is unlikely to spring to mind as a source of reliable information about complex issues, but scientists are using it to fly the flag for COVID-19 vaccines and other health topics. When we talk about vaccines as health professionals, people who are vehemently anti-vaccine can take it out of context for their agenda.
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The Husband-and-Wife Team Behind the Leading Vaccine to Solve Covid-19
NY Times
NOVEMBER 10, 2020
The German company BioNTech, founded by two scientists, has teamed up with Pfizer on a vaccine that was found to be more than 90 percent effective.
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COVID-19 immunity lasts eight months, say scientists: giving 'real hope' for long term vaccine protection
BioPharma Reporter
DECEMBER 23, 2020
People who have been infected with SARS-CoV-2 retain immune memory to protect against reinfection for 'at least eight months', according to Australian scientists. This research is the strongest evidence for the likelihood that vaccines against the virus will work for long periods," they say.
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UK orders extra 114 million COVID-19 vaccines to combat Omicron
Pharma Times
DECEMBER 2, 2021
Scientists and health experts have cautioned that the new variant could have the ability to bypass the effectiveness of vaccines that are currently available.
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Scientists produce 'DNA virus vaccine' to fight DNA viruses
Medical Xpress
NOVEMBER 18, 2022
Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.
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FDA staff take neutral stance on Moderna, J&J boosters ahead of two-day meeting
Bio Pharma Dive
OCTOBER 13, 2021
In briefing documents, agency scientists emphasized both vaccines still offer strong protection against severe COVID-19, but acknowledged potential for some added benefit with another dose.
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GSK, Sanofi, Takeda and scientists in Singapore partner for biologics
Pharmaceutical Technology
DECEMBER 7, 2022
BioPIPS plans to utilise research and innovation to enhance the biologics manufacturing expertise of Singapore, which comprises recombinant therapeutic proteins and vaccines. The solutions created through BioPIPS will also boost the country’s capacity for meeting the rising demand for biologics and vaccines throughout the world.
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Will the Vaccines Stop Omicron? Scientists Are Racing to Find Out.
NY Times
NOVEMBER 28, 2021
A “Frankenstein mix” of mutations raises concerns, but the variant may remain vulnerable to current vaccines. If not, revisions will be necessary.
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Scientists develop a cancer vaccine to simultaneously kill and prevent brain cancer
Medical Xpress
JANUARY 4, 2023
Scientists are harnessing a new way to turn cancer cells into potent, anti-cancer agents. The team tested their dual-action, cancer-killing vaccine in an advanced mouse model of the deadly brain cancer glioblastoma, with promising results. In the latest work from the lab of Khalid Shah, MS, Ph.D.,
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Moderna’s HIV vaccine prepped for trials in Africa
pharmaphorum
MAY 19, 2022
Moderna has joined forces with non-profit organisation IAVI on a third phase 1 trial of its candidate HIV vaccine in Africa, where the burden of the virus is still being keenly felt. There are hopes that its mRNA approach, which proved so effective against COVID-19, could succeed where traditional vaccine technologies have failed in HIV.
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COVID-19: Some ignored facts
World of DTC Marketing
APRIL 11, 2021
QUICK THOUGHT: People believe the COVID-19 vaccine was developed in less than a year but that’s not true. Based on the virus a number of vaccines targeting the spike protein were designed, tested in animal models and found to be quite promising against SARS and other coronavirus illnesses like Middle East respiratory syndrome.
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Next virus could be more lethal than COVID-19, warns Oxford vaccine creator
Pharma Times
DECEMBER 6, 2021
With the emergence of the new Omicron variant bringing into question the effectiveness of current vaccines, scientists caution that viruses will continue to evolve.
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Study points to route for 'one and done' flu vaccine
pharmaphorum
JULY 22, 2024
Scientists at OHSU in the US have developed a universal form of influenza vaccine that they say could protect against all strains of the virus
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Scientists may have solved an important part of the mystery of ultra-rare blood clots linked to adenovirus-based COVID-19 vaccines
Scienmag
DECEMBER 1, 2021
An international team of scientists believe they may have found a molecular mechanism behind the extremely rare blood clots linked to adenovirus COVID-19 vaccines.
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Scientists develop 20-subtype mRNA flu vaccine to protect against future flu pandemics
Medical Xpress
NOVEMBER 24, 2022
An experimental mRNA-based vaccine against all 20 known subtypes of influenza virus has provided broad protection from otherwise lethal flu strains in initial tests, and thus might serve one day as a general preventative measure against future flu pandemics, according to researchers from the Perelman School of Medicine at the University of Pennsylvania. (..)
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LJI scientists publish first head-to-head comparison of four COVID-19 vaccines
Scienmag
MAY 31, 2022
LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have published the first analysis of how four types of COVID-19 vaccines prepare the body to fight SARS-CoV-2.
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Celebrating Black History Month: Black Scientists that Have Revolutionized the Life Sciences
XTalks
FEBRUARY 15, 2024
In the life sciences, countless Black scientists, researchers and medical professionals have made groundbreaking discoveries that have significantly advanced our understanding of biology and medicine. They serve as inspiration for future generations of scientists from all backgrounds.
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Allergic reactions prompt Moderna COVID vaccine pause in California
pharmaphorum
JANUARY 18, 2021
Public health authorities in California are seeking a halt on dosing of one lot of Moderna’s COVID-19 vaccine after reports of allergic reactions at one immunisation clinic. The clinic in question switched to another lot of Moderna vaccine after closing for a few hours.
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Scientists find human antibodies that can block multiple coronaviruses including SARS-CoV-2
Medical Xpress
FEBRUARY 28, 2023
A team of scientists from Scripps Research and the University of North Carolina (UNC) has found antibodies in the blood of certain COVID-19 donors that can block infection from a broad set of coronaviruses—specifically, in people who have recovered from the virus and were then vaccinated.
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Scientists develop new precise therapeutic leukemia vaccine
Scienmag
OCTOBER 12, 2020
Credit: WEI Wei Exploration of new leukemia antigens and construction of appropriate delivery systems using FDA-approved material are important strategies for developing leukemia vaccines for clinic use.
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Top Research Scientists Suggest Needle-Free COVID-19 Vaccines Are on the Way
BioSpace
MARCH 17, 2021
According to an interview with Soumya Swaminathan, the WHO's chief scientist, the new investigational COVID-19 vaccines rely on alternative technologies and systems of delivery. Some include oral and nasal administration, while others use skin patches.
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