GSK hires away top Pfizer vaccine scientist
Bio Pharma Dive
NOVEMBER 30, 2021
Philip Dormitzer, who helped Pfizer develop shots for COVID-19, RSV and influenza, will become the British pharma's head of vaccine R&D next month.
Extreme Case of Man Who Had 217 COVID Vaccines Surprises Scientists
AuroBlog - Aurous Healthcare Clinical Trials blog
MARCH 12, 2024
That’s how many vaccines a man in Germany claims to have received for COVID-19 in just 29 months – and his body isn’t reacting the way some scientists thought it would. Two hundred and seventeen. The 62-year-old male from the city of Magdeburg made headlines a few years ago for his private and risky decision […]
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FDA weighs shift in COVID vaccination strategy
Bio Pharma Dive
JANUARY 23, 2023
Agency scientists are proposing to update COVID shots once a year to match circulating coronavirus strains, as well as simplifying current vaccination regimens.
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FDA review supports safety, efficacy of J&J coronavirus vaccine
Bio Pharma Dive
FEBRUARY 24, 2021
Agency scientists noted the shot's strong protection against severe COVID-19, even for the virus variant first detected in South Africa and known to weaken vaccine potency.
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Russia, with scant study data, approves coronavirus vaccine
Bio Pharma Dive
AUGUST 11, 2020
The shot, developed by the state-backed Gamaleya Research Institute, hasn't yet been tested in the large, placebo-controlled tests scientists emphasize are needed to prove a vaccine is protective.
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FDA names new head to vaccine review office
Bio Pharma Dive
SEPTEMBER 9, 2022
David Kaslow, the lead scientist at a global public health nonprofit, will succeed Marion Gruber, who retired last fall amid her dissent on the timing of COVID-19 vaccine boosters.
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Breakthrough Vaccine Shows High Protection Against Drug-Resistant Superbug in Mice
AuroBlog - Aurous Healthcare Clinical Trials blog
MAY 1, 2024
Scientists have developed a vaccine against a notorious drug-resistant superbug, targeting molecules on its surface that are also found on other bacteria and fungi.
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Malaria Could Be Eliminated by 2040: New Vaccine Offers Hope
AuroBlog - Aurous Healthcare Clinical Trials blog
OCTOBER 8, 2023
The World Health Organization has approved a new vaccine that scientists argue will be a game-changer in the fight against malaria, which kills half a million people in Africa every year.
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Valneva’s Lyme disease vaccine faces final clinical test in a sparse landscape
Pharmaceutical Technology
AUGUST 17, 2022
On August 8, Pfizer and Valneva announced the initiation of a Phase III study with their Lyme disease vaccine , bringing the prospect of an injection to prevent the condition disease one step closer to reality. This means that the vaccine works against multiple serotypes of the disease, she explains. A one-size-fits-all approach.
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Vaccine Makers Keep Safety Details Quiet, Alarming Scientists
NY Times
SEPTEMBER 13, 2020
Researchers say drug companies need to be more open about how vaccine trials are run to reassure Americans who are skittish about getting a coronavirus vaccine.
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Pfizer/BioNTech vaccine may work against new virus mutation, scientists say
pharmaphorum
JANUARY 8, 2021
The Pfizer/BioNTech vaccine appears to work against an important mutation in the new coronavirus variants causing havoc in the UK and South Africa, according to research from the drugs giant. The study team tested blood taken from people who had received the mRNA vaccine developed by BioNTech and Pfizer.
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DBT to support multi institutional CoEs for nano-vaccines and nano-adjuvants development
AuroBlog - Aurous Healthcare Clinical Trials blog
DECEMBER 14, 2022
The Department of Biotechnology (DBT) is extending support to the institutions and scientists to set up Centres of Excellence in the country for nano-vaccines and nano-adjuvants, to treat cancer and other diseases.The Department has invited Letters of Intent (LoIs) for ‘Setting up of CoE in Nano-Vaccines & Nano-Adjuvants’ for a period of five years (..)
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Scientists Explore SARS-CoV-2 Mega Vaccine
BioSpace
NOVEMBER 10, 2021
?Scientists are conducting research into the possibility of creating a vaccine that activates T cells that targets not just SARS-CoV-2 but also its variations, even the ones that cause common colds.
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Scientists behind mRNA Covid vaccines win Nobel Prize
BioPharma Reporter
OCTOBER 3, 2023
The Nobel Prize in medicine has been awarded to two scientists who developed the technology which led to the mRNA vaccines against COVID-19.
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Going all the way: Scientists prove that inhaled vaccines offer better protection and immunity than nasal sprays
Scienmag
JUNE 9, 2022
HAMILTON, June 10, 2022–McMaster University scientists who compared respiratory vaccine-delivery systems have confirmed that inhaled aerosol vaccines provide far better protection and stronger immunity than nasal sprays.
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Scientists and medics turn to TikTok to reassure public on vaccine safety
pharmaphorum
DECEMBER 17, 2020
Tik Tok is unlikely to spring to mind as a source of reliable information about complex issues, but scientists are using it to fly the flag for COVID-19 vaccines and other health topics. When we talk about vaccines as health professionals, people who are vehemently anti-vaccine can take it out of context for their agenda.
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The Husband-and-Wife Team Behind the Leading Vaccine to Solve Covid-19
NY Times
NOVEMBER 10, 2020
The German company BioNTech, founded by two scientists, has teamed up with Pfizer on a vaccine that was found to be more than 90 percent effective.
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COVID-19 immunity lasts eight months, say scientists: giving 'real hope' for long term vaccine protection
BioPharma Reporter
DECEMBER 23, 2020
People who have been infected with SARS-CoV-2 retain immune memory to protect against reinfection for 'at least eight months', according to Australian scientists. This research is the strongest evidence for the likelihood that vaccines against the virus will work for long periods," they say.
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UK orders extra 114 million COVID-19 vaccines to combat Omicron
Pharma Times
DECEMBER 2, 2021
Scientists and health experts have cautioned that the new variant could have the ability to bypass the effectiveness of vaccines that are currently available.
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Will the Vaccines Stop Omicron? Scientists Are Racing to Find Out.
NY Times
NOVEMBER 28, 2021
A “Frankenstein mix” of mutations raises concerns, but the variant may remain vulnerable to current vaccines. If not, revisions will be necessary.
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Scientists produce 'DNA virus vaccine' to fight DNA viruses
Medical Xpress
NOVEMBER 18, 2022
Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.
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Moderna’s HIV vaccine prepped for trials in Africa
pharmaphorum
MAY 19, 2022
Moderna has joined forces with non-profit organisation IAVI on a third phase 1 trial of its candidate HIV vaccine in Africa, where the burden of the virus is still being keenly felt. There are hopes that its mRNA approach, which proved so effective against COVID-19, could succeed where traditional vaccine technologies have failed in HIV.
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Study points to route for 'one and done' flu vaccine
pharmaphorum
JULY 22, 2024
Scientists at OHSU in the US have developed a universal form of influenza vaccine that they say could protect against all strains of the virus
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Scientists may have solved an important part of the mystery of ultra-rare blood clots linked to adenovirus-based COVID-19 vaccines
Scienmag
DECEMBER 1, 2021
An international team of scientists believe they may have found a molecular mechanism behind the extremely rare blood clots linked to adenovirus COVID-19 vaccines.
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Scientists develop 20-subtype mRNA flu vaccine to protect against future flu pandemics
Medical Xpress
NOVEMBER 24, 2022
An experimental mRNA-based vaccine against all 20 known subtypes of influenza virus has provided broad protection from otherwise lethal flu strains in initial tests, and thus might serve one day as a general preventative measure against future flu pandemics, according to researchers from the Perelman School of Medicine at the University of Pennsylvania. (..)
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Next virus could be more lethal than COVID-19, warns Oxford vaccine creator
Pharma Times
DECEMBER 6, 2021
With the emergence of the new Omicron variant bringing into question the effectiveness of current vaccines, scientists caution that viruses will continue to evolve.
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LJI scientists publish first head-to-head comparison of four COVID-19 vaccines
Scienmag
MAY 31, 2022
LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have published the first analysis of how four types of COVID-19 vaccines prepare the body to fight SARS-CoV-2.
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Scientists develop new precise therapeutic leukemia vaccine
Scienmag
OCTOBER 12, 2020
Credit: WEI Wei Exploration of new leukemia antigens and construction of appropriate delivery systems using FDA-approved material are important strategies for developing leukemia vaccines for clinic use.
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Top Research Scientists Suggest Needle-Free COVID-19 Vaccines Are on the Way
BioSpace
MARCH 17, 2021
According to an interview with Soumya Swaminathan, the WHO's chief scientist, the new investigational COVID-19 vaccines rely on alternative technologies and systems of delivery. Some include oral and nasal administration, while others use skin patches.
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The scientist behind Pfizer’s Covid vaccine says a flu pandemic is only a matter of time
STAT News
NOVEMBER 16, 2022
BOSTON — Even after leading the charge combating the worst pandemic in a century, vaccine researcher Kathrin Jansen doesn’t feel that she can relax. Another pandemic — this one based on an influenza virus — is inevitable, Jansen said at the annual STAT Summit on Tuesday. Read the rest…
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New RDIF Website Details Russia’s COVID-19 Vaccine as Global Phase III Trials Begin
BioSpace
AUGUST 13, 2020
Phase III clinical trials for Russia’s Sputnik V vaccine for COVID-19 began Wednesday, one day after the Russia Direct Investment Fund (RDIF) launched a new website to share the details of the vaccine with the public and scientists around the world.
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Regulators questioned integrity of Pfizer/BioNTech vaccine, leaked files show
pharmaphorum
MARCH 16, 2021
European regulators questioned the integrity of early batches of Pfizer/BioNTech’s mRNA vaccine, although the matter was resolved before approval, according to information leaked online following a cyberattack. As it conducted its analysis of the vaccine in December, the European Medicines Agency’s systems were targeted by unknown hackers.
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J&J single-shot COVID-19 vaccine shows early promise
pharmaphorum
JANUARY 15, 2021
J&J has announced early trial results that suggest its single-shot coronavirus vaccine provides a sustained response against the virus ahead of a phase 3 trial readout due later this month. Both of these vaccines require two doses, as does the most recently approved shot from Moderna, which is due to arrive in the UK in the spring.
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An mRNA vaccine strategy under study to fight the flu—as a shot and intranasal spray
Medical Xpress
DECEMBER 30, 2022
Messenger RNA vaccine technology, once an arcane area of research, became household terminology because of the COVID-19 pandemic, and now scientists are working on an mRNA flu vaccine strategy that, at least in this study, involves a first dose administered as a shot but a booster administered as an mRNA nasal spray.
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Lipid research may help solve COVID-19 vaccine challenges
Scienmag
APRIL 14, 2021
Credit: University of Texas at Dallas New research by University of Texas at Dallas scientists could help solve a major challenge in the deployment of certain COVID-19 vaccines worldwide — the need for the vaccines to be kept at below-freezing temperatures during transport and storage.
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Virus strain change should not affect COVID-19 vaccine candidates, say researchers
BioPharma Reporter
OCTOBER 15, 2020
Potential vaccines for COVID-19 should not be affected by changes in SARS-CoV-2 seen to date, nor are they likely to need to be redeveloped seasonally, according to Australian scientists.
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Altimmune begins trial of nasal vaccine for COVID-19
pharmaphorum
FEBRUARY 25, 2021
Pfizer/BioNTech’s mRNA vaccine against COVID is a technical marvel – but the ultra-cool temperatures required for storage and stability has been tricky to handle. The company announced a phase 1 trial is beginning of its nasal spray vaccine just as scientists in the UK said they are considering a similar approach.
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With monkeypox vaccine in high demand, NIH to test approaches to stretch supplies
STAT News
AUGUST 4, 2022
The global need for monkeypox vaccine outstrips the supply, and will likely continue to do so for quite some time. Scientists at the National Institutes of Health are getting ready to explore a possible work-around. Read the rest…
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Current vaccines teach T cells to fight Omicron
Scienmag
JANUARY 24, 2022
LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have found that four COVID-19 vaccines (Pfizer-BioNTech, Moderna, J&J/Janssen, and Novavax) prompt the body to make effective, long-lasting T cells against SARS-CoV-2. Credit: La Jolla Institute for Immunology LA JOLLA, CA—Scientists at […].
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STAT+: An mRNA vaccine for cancers associated with HPV shows promise in mice
STAT News
MARCH 3, 2023
The HPV vaccine is a slam dunk in preventing the vast majority of cancers related to the infection — namely tumors of the head and neck , anus, penis, vagina, and cervix. Everyone else must hope for other vaccines that scientists are developing to treat existing HPV-associated cancer.
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Middle-income countries have come up with a game-changing plan for COVID vaccines
NPR Health - Shots
JULY 18, 2022
and Europe spearhead COVID vaccines, other regions are left struggling to gain access. But now scientists from Latin America and Africa are collaborating on mRNA technology. As the U.S.
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A 3D printed vaccine patch offers vaccination without a shot
Scienmag
SEPTEMBER 24, 2021
Scientists at Stanford University and the University of North Carolina at Chapel Hill have created a 3D-printed vaccine patch that provides greater protection than a typical vaccine shot. Scientists at Stanford University and the University of North Carolina at […]. CHAPEL HILL, N.C.
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Moderna and U.S. at Odds Over Vaccine Patent Rights
NY Times
NOVEMBER 9, 2021
Moderna’s patent application names several employees as the sole inventors of a crucial component of its coronavirus vaccine, excluding three government scientists.
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New method to assist fast-tracking of vaccines for pre-clinical tests
Scienmag
JANUARY 18, 2021
Novel tuberculosis vaccine demonstrated strong immune response in mice Credit: University of Sydney Scientists in Australia have developed a method for the rapid synthesis of safe vaccines, an approach that can be used to test vaccine strategies against novel pandemic pathogens such as SARS-CoV-2, the virus that causes COVID-19.
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