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Merck will pair Keytruda (pembrolizumab) with bempegaldesleukin (NKTR-214) – known as bempeg for short – in a phase 2/3 trial involving patients with squamous cell carcinoma of the head and neck (SCCHN) that if positive could support regulatory filings. That was signed for $1.8
Louis and Massachusetts General Hospital/Harvard Medical School in Boston have received a seven-year, $22 million grant from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) to help lead a multicenter clinical trial evaluating whether a novel immunosuppressant can […].
National Institutes of Health failed to ensure that results of roughly half of clinical trialsfunded by the agency — both those conducted by its own scientists and outside researchers — were reported to a federal database during a recent two-year period, a new government review has found.
The NIH this month published notice of a funding opportunity to support the next round of pragmatic clinical trials within the NIH-DoD-VA Pain Management Collaboratory (PMC). Read the full notice of funding opportunity (RFA-AT-24-004). The PMC was established in 2017 with an initial cohort of 11 pragmatic trials.
On June 22, 2022, the Canadian Institutes of Health Research ( CIHR ) announced the launch of the Clinical TrialsFund ( CTF ), which will inject funding into Canada’s clinical trials environment. The Clinical TrialsFund. Clinical Trials Training Platforms ( CTTP ). Clinical Trials Projects.
Adding Eli Lilly’s rheumatoid arthritis drug Olumiant (baricitinib) and Gilead Sciences’ remdesivir reduces recovery time in COVID-19 patients compared to remdesivir alone, says a new trial. The post Trial backs Lilly’s Olumiant plus remdesivir as combo COVID-19 therapy appeared first on.
While a prolonged, 15-day regimen of Paxlovid is safe, it appears to be ineffective at lowering the symptoms of long COVID, according to results of a Phase II trialfunded by Pfizer and conducted by Stanford Medicine.
The trials, funded by the American Heart Association, will harness the companyâs Verisense wearable sensor platform to examine brain-heart health links.
The adoption of decentralized clinical trial (DCT) approaches has increased exponentially. Tools such as electronic consent, telehealth appointments and wearable devices have enabled investigators to contact trial participants virtually. What are some barriers to adopting DCT methods in oncology trials?
A clinical trialfunded by the National Institutes of Health has found that giving peanut oral immunotherapy to highly peanut-allergic children ages 1 to 3 years safely desensitized most of them to peanut and induced remission of peanut allergy in one-fifth. The immunotherapy consisted of a daily oral dose of peanut flour for 2.5
The first patients have been dosed in a trial of two AstraZeneca antibodies, collectively known as AZD7442, that are being developed to both treat and prevent coronavirus infections. The phase 1 trial – funded by the US government – will take place in the UK and will test the safety of AZD7442 and its pharmacokinetic profile.
, announced its intent to publish a new funding opportunity for cooperative research that will accelerate implementation of nonopioid interventions for chronic pain management in rural and remote populations. The funding opportunity announcement is expected to be published in fall 2022, with an expected application due date in winter 2022.
Optimizing clinical trial access for potential patients is a critical goal for researchers and sponsors. Decentralized clinical trials (DCTs) can meet that need, but they come with some challenges. Designing a DCT comes with certain challenges of course, particularly when proposing to utilize outside groups or locations for the trial.
Rigorous studies to build on earlier efforts to test the experimental treatment Two randomized, placebo-controlled clinical trialsfunded by the National Institutes of Health (NIH) are expanding enrollment to further evaluate convalescent plasma as a treatment for patients hospitalized with COVID-19.
Synedgen Initiates Clinical Trial Assessing Combination of SynePure and Catasyn for the Treatment of Partial Thickness Burns Synedgen Initiates Clinical Trial Assessing Combination of SynePure and Catasyn for the Treatment of Partial Thickness Burns – Trialfunded by Defense Health … Continue reading →
The National Institute of Nursing Research (NINR) will host a webinar for its recent request for applications, “ RFA-NR-23-001 , HEAL Initiative: Prevention and Management of Chronic Pain in Rural Populations (UG3/UH3 Clinical Trial Required).” The webinar is optional and not required for application submission.
The 1-year pilot grant awards will fund up to $175,000 in direct costs for pilot studies that aim to generate preliminary data for full-scale embedded pragmatic clinical trials of nonpharmacologic interventions in healthcare systems for persons living with Alzheimer disease and related dementias and/or their care partners.
Regeneron is considering an emergency filing for its antibody cocktail REGEN-COV to protect people against COVID-19 after early trial results showed it conferred 100% protection against symptomatic infection. In the placebo group patients there were 44 viral shedding weeks compared with nine in the treatment arm.
15, 2021 — An inhaled medication might make every day physical activity a bit easier for patients with serious scarring of the lungs, a new clinical trial finds. Right now, no medication is approved specifically for pulmonary hypertension caused by ILD, said Dr. Steven Nathan, senior researcher on the new trial. FRIDAY, Jan.
Elliott informed those in attendance that for the next five years, with about £5 billion in funding for pipelines across a network of research and institute centres in clinical trials, that the aim is for everyone to live a life free of cancer. And in the UK over 30% of clinical trialsfunded has one European partner at least.
A Democratic lawmaker is demanding to know what steps the Food and Drug Administration and the National Institutes of Health are taking to ensure that results of clinical trialsfunded by the government are reported to a federal database. In a letter sent on Thursday, U.S. Frank Pallone (D-N.J.)
National Institutes of Health will take to ensure that results of clinical trialsfunded by the agency — both those conducted by its own scientists and outside researchers — are reported to a federal database. A group of Republican senators is demanding to know what steps the U.S. Department of Health and Human Services.
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