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Government of Canada invests in clinical trial development in Canada through the Clinical Trials Fund

Pharma in Brief

On June 22, 2022, the Canadian Institutes of Health Research ( CIHR ) announced the launch of the Clinical Trials Fund ( CTF ), which will inject funding into Canada’s clinical trials environment. The Clinical Trials Fund. Clinical Trials Training Platforms ( CTTP ). Clinical Trials Projects.

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Nektar lifted by Merck alliance for bempeg, new trial funding

pharmaphorum

Merck will pair Keytruda (pembrolizumab) with bempegaldesleukin (NKTR-214) – known as bempeg for short – in a phase 2/3 trial involving patients with squamous cell carcinoma of the head and neck (SCCHN) that if positive could support regulatory filings. That was signed for $1.8

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Reducing lung transplant rejection aim of clinical trial funded with $22 million grant

Scienmag

Louis and Massachusetts General Hospital/Harvard Medical School in Boston have received a seven-year, $22 million grant from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) to help lead a multicenter clinical trial evaluating whether a novel immunosuppressant can […].

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Pfizer’s Paxlovid Ineffective Against Long COVID Using 15-Day Regimen: Study

BioSpace

While a prolonged, 15-day regimen of Paxlovid is safe, it appears to be ineffective at lowering the symptoms of long COVID, according to results of a Phase II trial funded by Pfizer and conducted by Stanford Medicine.

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STAT+: ‘A blind eye’: NIH fails to ensure clinical trial results are reported and funds researchers who don’t file results

STAT News

National Institutes of Health failed to ensure that results of roughly half of clinical trials funded by the agency — both those conducted by its own scientists and outside researchers — were reported to a federal database during a recent two-year period, a new government review has found.

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July 31, 2023: NIH Announces Funding Opportunity for Pain Management Collaboratory Pragmatic Trials

Rethinking Clinical Trials

The NIH this month published notice of a funding opportunity to support the next round of pragmatic clinical trials within the NIH-DoD-VA Pain Management Collaboratory (PMC). Read the full notice of funding opportunity (RFA-AT-24-004). The PMC was established in 2017 with an initial cohort of 11 pragmatic trials.

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Decentralized Oncology Trials: Interview with Dr. Crystal S. Denlinger, CSO at NCCN

XTalks

The adoption of decentralized clinical trial (DCT) approaches has increased exponentially. Tools such as electronic consent, telehealth appointments and wearable devices have enabled investigators to contact trial participants virtually. What are some barriers to adopting DCT methods in oncology trials?

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